Table of Contents

Introduction - Rini/Campbell
1: Pathology - (Zhou, CCF)
2: Epidemiology and Screening of RCC (Godley)
3: Diagnosis and Management of Inherited RCC(Nathanson/Stephenson)
4: Genetics of Sporadic RCC (Bin Teh)
5: Imaging Techniques (Herts)
6: Management of Small Renal Masses
a: Biopsy (Uzzo)
b: Non-invasive Techniques (Matin)
c: Partial Nephrectomy (Novick)
7: Prognostic Factors in Localized RCC (Pantuc, Belldegrun)
8: Radical Nephrectomy for Localized RCC (Samir Taneja - NYU)
9: Surgical Management of Locally-Advanced RCC (Wood)
10: Adjuvant Therapy in RCC (Eisen-Caimbridge)
11: Prognostic Factors in Metastatic RCC (Choueiri-CCF)
12: Immunobiology of Metastatic RCC (Jim Finke – CCF)
13: Immunotherapy in Metastatic RCC (David McDermott – BI)
14: Angiogenesis Biology in Metastatic RCC (Kim Rathmell – UNC)
15: Anti-VEGF Therapy in Metastatic RCC
a: VEGF Ligand-binding Agents (Rini/Rathmell)
b: Therapeutic Inhibition of VEGF Receptor (Oliver Rixe – France)
16: Akt Pathway Biology in Metastatic RCC (Dan George – Duke)
17: Therapeutic mTOR Inhibition in Metastatic RCC (Gary Hudes – FCCC)
18: Future Therapeutics in Metastatic RCC (Keith Flaherty - Penn)
19: Surgical Management of Metastatic RCC (Evans, Rini and Campbell)
20: Supportive Care in Metastatic RCC
a: Biphosphonates (Michelson - MGH)
b: Management of CNS Metastases (Hutson - Baylor)
c: Palliative Care Considerations (Davis - CCF)

About the Author

Brian I. Rini, MD, Associate Professor Department of Solid Tumor Oncology and Urology, Cleveland Clinic Taussig Cancer Center, Associate Professor of Medicine Cleveland Clinic Foundation/ Case Western Reserve, University Lerner College of Medicine Cleveland, OH.

Steven C. Campbell, MD, PhD Professor of Surgery, Section of Urological Oncology Glickman Urological Institute Cleveland Clinic Foundation Cleveland, OH.