Table of Contents

Applications.- Comparing Time Series through Event Clustering.- Visual Knowledge-Based Metaphors to Support the Analysis of Polysomnographic Recordings.- A Bio-inspired Proposal for Focus Attention While Preserving Information.- Modelling Fed-Batch Fermentation Processes: An Approach Based on Artificial Neural Networks.- Treatment and Diagnosis.- New Principles and Adequate Control Methods for Insulin Dosage in Case of Diabetes.- A Framework for CBR Development and Experimentation with Application to Medical Diagnosis.- Identification of Relevant Knowledge for Characterizing the Melanoma Domain.- TAT-NIDS: An Immune-Based Anomaly Detection Architecture for Network Intrusion Detection.- Genome.- Novel Computational Methods for Large Scale Genome Comparison.- Improving Literature Searches in Gene Expression Studies.- Implementing an Interactive Web-Based DAS Client.- Data Integration Issues in the Reconstruction of the Genome-Scale Metabolic Model of Zymomonas Mobillis.- Microarray 1.- Applying CBR Systems to Micro Array Data Classification.- Multiple-Microarray Analysis and Internet Gathering Information with Application for Aiding Medical Diagnosis in Cancer Research.- Evolutionary Techniques for Hierarchical Clustering Applied to Microarray Data.- Beds and Bits: The Challenge of Translational Bioinformatics.- Microarray 2.- A Matrix Factorization Classifier for Knowledge-Based Microarray Analysis.- Named Entity Recognition and Normalization: A Domain-Specific Language Approach.- BIORED - A Genetic Algorithm for Pattern Detection in Biosequences.- A Recursive Genetic Algorithm to Automatically Select Genes for Cancer Classification.- Proteins and Cells.- On Mining Protein Unfolding Simulation Data with Inductive Logic Programming.- A Knowledge Discovery Method for the Characterization of Protein Unfolding Processes.- Design of New Chemoinformatic Tools for the Analysis of Virtual Screening Studies: Application to Tubulin Inhibitors.- Multi-Objective Optimization of Biological Networks for Prediction of Intracellular Fluxes.- Mathematical Models.- SimSearch: A New Variant of Dynamic Programming Based on Distance Series for Optimal and Near-Optimal Similarity Discovery in Biological Sequences.- Tuning Parameters of Evolutionary Algorithms Using ROC Analysis.- Speeding-Up ACO Implementation by Decreasing the Number of Heuristic Function Evaluations in Feature Selection Problem.- Global Sensitivity Analysis of a Biochemical Pathway Model.- Improving a Leaves Automatic Recognition Process Using PCA.