I. The Current Global Surgical Care Paradigm

1.1 The Global Surgical Burden of Disease: A Global Health Paradigm

1.2 Surgically Avertable Deaths: A Silent Premise

1.3 Defining Essential Surgical Conditions in LMICs

1.4 Disparity of Surgical Service Provision in LMICs

1.5 Disparities in Provisional Access to Surgical Instruments and Supplies in LMICs

II. Surgical Interventions in Global Health: Social and Economic Implications

2.1 Surgery: A Highly Cost-Effective Health Intervention

2.2 The Economic Returns of Surgical Interventions

2.3 Catastrophic Healthcare Expenditures: A Perspective

2.4 The Social Returns of Surgical Interventions

III. 3-Dimensional Printing and Rapid Prototyping: Implications for Global Health

3.1 The Dawn of Disruptive Innovations and Frugal Engineering

3.2 3-Dimensional Printing: An Introduction to Rapid Device Prototyping and Fabrication

3.3 The RepRap Rapid Prototyping Device and Fused Deposition Modeling

IV. 3-Dimensional Device Fabrication: Bio-Based Materials and Thermoplastics

4.1 Bio-Based Thermoplastic Polymers in 3D Printing

4.2 Polylactic-Acid: Bio-Based Thermoplastic Polymer Properties and Medical Device

Applications

4.3 Acrylonitrile Butadiene Styrene Thermoplastics: Mechanical and Chemical Profile

4.4 Chemical and Mechanical Profile Modification of Bio-Based Materials: Polymeric Blending

and Natural Polymer Enhancement

V. 3-Dimensional Printing of Medical Devices and Supplies

5.1 The Current State of 3-Dimensional Printing: Fabrication of Medical Devices and Supplies

5.2 Fabrication of High-Utility Integrative Surgical Toolkits

5.3 3-Dimensional Printing in the Surgical Field: Field Applications and Considerations

VI. 3-Dimensional Printing: Interventional Capacities in the Global Health Arena

6.1 3D Printed Instrument and Medical Supply Price Competencies

6.2 Barriers to Entry and Adoption of Medical Device Innovations in LMICs

6.3 3D Printing: A Paradigm Shift in the Global Medical Device and Humanitarian Supply Chain

6.4 3D Printing: Global Open Source Blueprint and Information Dissemination

6.5 The Future of Bio-Based Materials Development in Medical Device Fabrication