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Advances in Tracer Methodology
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Table of Contents

Early History of Carbon-14.- Methods for Labeling Compounds.- Conditions for High Yield in the Labeling of Hydrocarbons by Exchange.- C14-Labeling Using Carbene Insertion—Application to Saturated Hydrocarbons.- Biosynthesis of Labeled Carbohydrates and Other Compounds of Biochemical Interest.- The Preparation of Labeled Albumins for Turnover Studies.- The Biosynthesis of C14- and H3-Labeled Insulin.- Purification of High Specific Activity Acetic — H3 Anhydride.- Special Analytical Techniques.- Automatic Counting of Radioactivity on Two-Dimensional Paper Chromatograms.- A Convenient Method for the Determination of Metabolically Liberated C14O2.- Liquid Scintillation Counting of C14-Labeled Amino Acids on Paper, Using Trinitrobenzene- 1-Sulfonic Acid, and an Improved Combustion Apparatus.- Zonal Scanning of Thin-Layer Chromatograms.- Continuous Scintillation Counting of Amino Acid Analyzer Column Eluates.- Some Techniques of Radioactive Gas Chromatography for Lipid Research.- The Microchemical Identification of Steroids from Biological Media.- Isotope Fractionation in the Absorption Chromatography of Doubly-Labeled Compounds.- Quench Correction by Automatic External Standardization.- Biochemical Applications.- Analytical Studies Using Low Levels of Carbon-14 and Tritium: A Method for Determining the Labeling Pattern in myo-Inositol.- Multiple Labeling to Determine Metabolic Pathways: Use of Labeling Ratios.- Diffusion of Radioactively Labeled Molecules in Heart Muscle.- Use of Labeled Nonmetabolized Amino Acids in Biochemical Research.- The Use of DMO-2-C14 (5,5,- Dimethyl- 2,4-Oxazolidinedione-2-C14) and Inulin-Carboxyl-C14 for Measurement of Intracellular pH.- Clinical Applications.- AEC Licensing of Radioisotopes for Clinical Research.- The Preparation ofRadioactive Chemicals for Clinical Use.- Clinical Applications of Aldosterone In Vivo Secretion Rate.- Steroid Secretory Mixtures in Man.- Isotopic Methods for Steroids in Human Blood.- Estimation of Alternative Metabolic Pathways of Catecholamines in Man.- Use of Tracers in the Study of Biogenic Amine Compartments.- Evaluation of Rates of Secretion and of Interconversion of Steroid Hormones.- Diisopropylfluorophosphate-P32 (DFP-P32) as a Label for Granulocytes.- Clinical Use of Liquid-Type Whole-Body Radioactivity Detectors.- Paired Labeling with I125 and I131.- The In Vivo Use of Doubly-Labeled Glucose to Determine Cerebral Metabolism in Humans.- Carbon-14 Fat Oxidation Test: A New Method for Measuring Fat Utilization in the Human.- Health Physics.- Coordinated Design of Radioisotope Laboratories.

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