Table of Contents

1. Principles of allostasis: optimal design, predictive regulation, pathophysiology and rational therapeutics Peter Sterling; 2. Protection and damaging effects of the mediators of stress and adaptation: allostasis and allostatic load Bruce S. McEwen; 3. Merging of the homeostatic theory with the concept of allostatic load David S. Goldstein; 4. Operationalizing allostatic load Burton Singer, Carol D. Ryff and Teresa Seeman; 5. Drug addiction and allostasis George F. Koob and Michael LeMoal; 6. Adaptive fear and the pathology of anxiety and depression: an allostatic framework Jeffrey B. Rosen and Jay Schulkin; 7. A chronobiological perspective on allostasis and its application to shift work Ziad Boulos and Alan M. Rosenwasser; 8. Allostatic load and life cycles: implications for neuroendocrine control mechanisms John C. Wingfield; 9. Commentary: viability as opposed to stability: an evolutionary perspective on physiological regulation Michael L. Power.

Promotional Information

First published in 2005, this book introduces the concept of allostasis and places it within the context of traditional homeostatic regulation.

Reviews

Review of the hardback: 'This book ... is very welcome as it goes a good way towards introducing readers of all levels to the concept ... it is well balanced ... this book will be an important text for those who want to know more.' Biologist