Table of Contents

Introduction.- Historical Aspects of the Diagnosis of Death.- The Determination of Brain Death.- Legal Aspects of Declaration of Brain Death and Organ Donation.-Ethical Aspects of Declaration of Brain Death and Organ Donation.- Pathophysiology of Brain Death in Small Animal Models.-Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models.-The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease.-The Inflammatory Response to Brain Death.- The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers.-Brain-Death–Induced Inflammation: Possible Role of the Cholinergic Anti-Inflammatory Pathway.- Innate Immunity and Injury During Brain Death: Opportunities for Intervention.- Selection of the Brain-Dead Potential Organ Donor.- Infectious Disease Aspects of the Brain-Dead Potential Organ Donor.- Malignancy in the Brain-Dead Organ Donor.- EarlyClinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor.- Assessment, Monitoring, and Management of the Brain-Dead Potential Organ Donor.- Assessment, Monitoring and Management of Brain-Dead Potential Organ Donors in Europe.- Current Management of Brain Dead Donors in Australia.- Management of the Brain-Dead Organ Donor—Perspectives of the Transplant Coordinator.-Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors.- Impact of Brain Death on Storage of the Heart.- Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies.- Functional Repair of Brain Death-Induced Injury.-Functional Repair of Brain-Death-Injured Donor Lungs.- Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor.- Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor.-Maximizing Utilization of the Potential Deceased Donor—The Challenge Continues.

Introduction.- Historical Aspects of the Diagnosis of Death.- The Determination of Brain Death.- Legal Aspects of Declaration of Brain Death and Organ Donation.-Ethical Aspects of Declaration of Brain Death and Organ Donation.- Pathophysiology of Brain Death in Small Animal Models.-Pathophysiology of Brain Death and Effects of Hormonal Therapy in Large Animal Models.-The Efficacy of Thyroid Hormone Therapy in Brain-Dead Heart Donors: A Review of Thyroid Function in Health and Disease.-The Inflammatory Response to Brain Death.- The Influence of Brain Death and Intensive Care Management on Donor Organs: Assessment of Inflammatory Markers.-Brain-Death–Induced Inflammation: Possible Role of the Cholinergic Anti-Inflammatory Pathway.- Innate Immunity and Injury During Brain Death: Opportunities for Intervention.- Selection of the Brain-Dead Potential Organ Donor.- Infectious Disease Aspects of the Brain-Dead Potential Organ Donor.- Malignancy in the Brain-Dead Organ Donor.- Early Clinical Experience of Hormonal Therapy in the Brain-Dead Potential Organ Donor.- Assessment, Monitoring, and Management of the Brain-Dead Potential Organ Donor.- Assessment, Monitoring and Management of Brain-Dead Potential Organ Donors in Europe.- Current Management of Brain Dead Donors in Australia.- Management of the Brain-Dead Organ Donor—Perspectives of the Transplant Coordinator.-Surgical Aspects of Thoracic and Abdominal Organ Procurement from Brain-Dead Donors.- Impact of Brain Death on Storage of the Heart.- Impact of Brain Death on Abdominal Organs and Allograft Preservation Strategies.- Functional Repair of Brain Death-Induced Injury.-Functional Repair of Brain-Death-Injured Donor Lungs.- Thyroid Hormone Therapy to the Recipient of a Heart from a Brain-Dead Donor.- Current and Potential Future Trends in the Management of the Brain-Dead Organ Donor.-Maximizing Utilization of the Potential Deceased Donor—The Challenge Continues.