Table of Contents

Part I Historical Overview of Cancer and Vitamin C. 1. Introduction to Vitamin C and Cancer Clinical Studies: A Historical Perspective. Part II Mechanims of Action for Vitamin C in Cancer. 2. High-Dose Intravenous Ascorbate as a Pro-Oxidant Inducing Cancer Cell Death. 3. Pharmacological Ascorbate Influences Multiple Cellular Pathways Preferentially in Cancer Cells. 4. Ascorbate and the Hypoxic Response in Cancer. 5. Pharmacological Ascorbate as a Radiosensitizer. 6. Vitamin C and Somatic Cell Reprogramming. Part III Vitamin C and Cancer Clinical Studies. 7. Vitamin C and Cancer: An Overview of Recent Clinical Trials. 8. Orthomolecular Approaches for the Use of Intravenous Vitamin C: Administration by Integrative and Naturopathic Doctors.

About the Author

Qi Chen, PhD, Associate Professor, Department of Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical Center, Kansas, City, USA.

Margareet C.M. Vissers, PhD, Research Professor, Department of Pathology and Biomedical Science at the University of Otago, Christchurch, New Zealand.