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Cell-Penetrating Peptides - Design, Development and Applications
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Table of Contents

Introduction

PART 1: DESGIN OF CPPS
Classification
Tat
Penetration
Guanidino transporter
Arg-rich peptides
Transportan
Hydrophobic peptides
Foldamers

PART 2: MECHANISM OF CPPS
Peptide structure
Cellular uptake
Endosomal escape
Pharmacokinetics

PART 3: DELIVERY TOOLS
Drug delivery
Peptide & protein delivery
Nucleic acid delivery
Polymeric micelles
Lipid-based nanoparticles

PART 4: APPLICATIONS
Oral delivery
Intranasal delivery
Clinical trials
CPPs in Plants

About the Author

Makoto Oba, Professor of Medical Chemistry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan. He has authored more than 100 scientific publications and has received several awards, including the Incentive Award in Synthetic Organic Chemistry.

Yosuke Demizu, Head of Division of Organic Chemistry, National Institute of Health Sciences (NIHS), Japan. He has published more than 150 scientific articles and is the recipient of several awards, such as the Japanese Peptide Society Award for Young Investigators.

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