Table of Contents

Chemokine Physiology.- The Function of Chemokines in Health and Disease.- Chemokine Receptors and Ligand Specificity.- Tumor Infiltration by Leukocytes.- Tumors as a Paradigm for the In Vivo Role of Chemokines in Leukocyte Recruitment.- Novel Monocyte Chemoattractants in Cancer.- Modulation of Host Responses to Cancer.- Natural Killer Cell-Chemokine Interactions.- Tumor Infiltration by Monocytes and the Antitumor Effects of Monocyte Chemoattractant Protein-1.- Interactions Between Chemokines and Other Cytokines in Host Response to Tumor.- Chemokines and Tumor Growth, Metastasis, and Angiogenesis.- Chemokine Modulation of Tumor Cell Physiology.- C-X-C Chemokines and Lung Cancer Angiogenesis.- The Role of Melanoma Growth-Stimulatory Activity in Melanoma Tumorigenesis and Angiogenesis.- Chemokines and Specific Malignancies.- Chemokines and Gynecologic Malignancies.- The Possible Role of Chemokines in HPV-Linked Carcinogenesis.- Chemokines and Central Nervous System Malignancies.- Chemokines and Helicobacter pylori Infection.- Chemokines and Stem Cell Proliferation.- Chemokines and Hematopoiesis.- Macrophage Inflammatory Protein-1? and Stem Cell Inhibition.

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". . .succeeds in bringing to the fore the important notion of whether chemokine action in tumor development should be antagonized or promoted for therapeutic purpose. . .should be well read."-Cell

". . .a detailed account of what is known of the biology of chemokines in cancer and it provides a very useful summary of the topic."-Molecular Pathology

"...this book is a good collection on a complex subject. It should be useful for both beginners and experts." -Cell Biology International