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Clinical Endocrinology and Diabetes at a Glance
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Table of Contents

Preface vii Part 1 Introduction 1 1 Introduction to endocrinology 2 Part 2 Disorders of the hypothalamic-pituitary axis 5 2 The hypothalamic-pituitary axis and its assessment 6 3 Acromegaly 8 4 Cushing's syndrome 10 5 Hypopituitarism and non-functioning pituitary adenomas 12 6 Prolactinoma and hyperprolactinaemia 14 Part 3 Disorders of thirst and fluid balance 17 7 Hypernatraemia and diabetes insipidus 18 8 Hyponatraemia and SIADH 20 Part 4 Thyroid disorders 23 9 Thyroid function 24 10 Hyperthyroidism: clinical presentation and investigation 26 11 Hyperthyroidism: management and ophthalmopathy 28 12 Hyperthyroidism: special circumstances 30 13 Hypothyroidism 32 14 Goitre, thyroid nodules and cancer 34 Part 5 isorders of calcium homeostasis 37 15 Physiology of calcium, PTH and vitamin D metabolism 38 16 Hypercalcaemia 40 17 Hypocalcaemia 42 18 Osteoporosis 44 Part 6 Disorders of the adrenal gland 47 19 Steroid physiology and biochemical assessment 48 20 Adrenal insufficiency 50 21 Adrenocortical tumours 52 22 Disorders of the adrenal medulla 54 Part 7 Disorders of the reproductive system 57 23 Physiology of the reproductive system 58 24 Growth, puberty and sexual differentiation 60 25 Menstrual disturbance 62 26 Hyperandrogenism 64 27 Menopause and HRT 66 28 Male hypogonadism 68 29 Gynaecomastia 70 30 Infertility 72 Part 8 Neuroendocrine tumours 75 31 Neuroendocrine tumours 76 32 Neuroendocrine tumours: management 78 33 Inherited endocrine tumour syndromes 80 34 Spontaneous hypoglycaemia 82 Part 9 Endocrine emergencies 85 35 Adrenal crisis 86 36 Pituitary apoplexy 88 37 Myxoedema coma 90 38 Thyroid storm 92 39 Acute hyponatraemia 94 40 Severe hypercalcaemia 96 41 Acute hypocalcaemia 98 Part 10 Diabetes mellitus 101 42 Overview 102 43 Diagnosis and monitoring 104 44 Classification 106 45 Type 1 diabetes: aetiology and clinical presentation 108 46 Type 1 diabetes: insulin and other therapies 110 47 Type 2 diabetes: aetiology and clinical presentation 112 48 Type 2 diabetes: treatment 114 49 Macrovascular complications 116 50 Microvascular complications 118 51 Diabetic foot disease 120 52 Diabetic ketoacidosis 122 53 Hyperglycaemic hyperosmolar state 124 54 Hypoglycaemia 126 55 Peri-operative management 128 56 Management of acute illness 131 57 Insulin infusions 134 58 Pregnancy and diabetes 136 59 Genetics of diabetes 138 60 The multidisciplinary team 140 61 Lipid disorders 142 62 Appetite and weight 144 63 Obesity and anorexia 146 Index 148

About the Author

Dr Aled Rees, Consultant Endocrinologist, School of Medicine, Cardiff University Dr Miles Levy, Consultant Endocrinologist, University Hospitals of Leicester Dr Andrew Lansdown, Consultant Endocrinologist, University Hospital of Wales, Cardiff

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