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Clinical Handbook of Psychotropic Drugs


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Table of Contents

Antidepressants Selective Serotonin Reuptake Inhibitors (SSRI) * Norepinephrine Dopamine Reuptake Inhibitor (NDRI) * Serotonin Norepinephrine Reuptake Inhibitor (SNRI) * Serotonin-2 Antagonists / Reuptake Inhibitors (SARI) * Serotonin-1A Agonist/Serotonin Reuptake Inhibitor (SPARI) * Serotonin Modulator and Stimulator (SMS) * Noradrenergic / Specific Serotonergic Antidepressants (NaSSA) * Nonselective Cyclic Antidepressants * Monoamine Oxidase Inhibitors * Reversible Inhibitor of MAO-A (RIMA) * Irreversible Monoamine Oxidase (A&B) Inhibitors (MAOIs) * Irreversible MAO-B Inhibitor * Effects of Antidepressants on Neurotransmitters / Receptors * Pharmacological Effects of Antidepressants on Neurotransmitters / Receptors * Frequency of Adverse Reactions to Antidepressants at Therapeutic Doses * Antidepressant Doses and Pharmacokinetics * Switching Antidepressants * Antidepressant Augmentation Strategies Electroconvulsive Therapy (ECT) Bright Light Therapy (BLT) Repetitive Transcranial Magnetic Stimulation (rTMS) Antipsychotics Second-Generation Antipsychotics / SGAs * Third-Generation Antipsychotic / TGA * 5-HT21 Inverse Agonist Antipsychotic * First- Generation Antipsychotics / FGAs * Effects of Antipsychotics on Neurotransmitters / Receptors * Pharmacological Effects of Antipsychotics on Neurotransmitters / Receptor Subtypes * Relative Tolerability Profiles of Anti-psychotics * Frequency of Adverse Reactions to Antipsychotics at Therapeutic Doses * Antipsychotic Doses and Pharmacokinetics (Oral and Short-Acting Injections) * Comparison of Long-Acting IM Antipsychotics * Switching Antipsychotics * Antipsychotic Augmentation Strategies Antipsychotic-Induced Extrapyramidal Side Effects and Their Management Extrapyramidal Adverse Effects of Antipsychotics * Treatment Options for Extrapyramidal Side Effects * Effects on Extrapyramidal Symptoms * Comparison of Agents for Treating Acute Extrapyramidal Side Effects * Doses and Pharmacokinetics of Agents for Treating Acute Extrapyramidal Side Effects Anxiolytic (Antianxiety) Agents Benzodiazepines * Comparison of the Benzodiazepines * Buspirone Hypnotics / Sedatives L-Tryptophan * Comparison of Hypnotics / Sedatives Mood Stabilizers Lithium * Anticonvulsants * Comparison of Anticonvulsants * Frequency of Adverse Reactions to Mood Stabilizers at Therapeutic Doses Drugs for ADHD Psychostimulants * Atomoxetine * Comparison of Drugs for ADHD * 2 Agonists * Augmentation Strategies in ADHD Drugs for Treatment of Dementia Cholinesterase Inhibitors * Memantine * Comparison of Drugs for Treatment of Dementia Sex-Drive Depressants Comparison of Sex-Drive Depressants Drugs of Abuse Alcohol * Stimulants * Hallucinogens * Opioids * Inhalants / Aerosols * Gamma-hydroxybutyrate (GHB) / Sodium Oxybate * Flunitrazepam (Rohypnol) * Nicotine / Tobacco Treatment of Substance Use Disorders Acamprosate * Disulfiram * Naltrexone * Buprenorphine * Methadone * Pharmacotherapy for Nicotine / Tobacco Use Disorder * Comparison of Treatments for Nicotine / Tobacco Use Disorder Unapproved Treatments of Psychiatric Disorders Adrenergic Agents * Anti-Inflammatory Agents * Dopaminergic Agents * GABA Agents / Anticonvulsants * Hormones * NMDA Agents * 5-HT3 Antagonists * Miscellaneous Natural Health Products Pharmacogenomic Information for Common Psychotropic Drugs Glossary Drug Use in Pregnancy and Effects on Breast Milk Patient Information Sheets Appendix: Neuroscience-Based Nomenclature Index of Drugs

About the Author

Ric M. Procyshyn; BScPharm, MSc, PharmD, PhD; Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada; British Columbia Mental Health & Addictions Research Institute, Vancouver, BC, Canada. Kalyna Z. Bezchlibnyk-Butler; BScPharm, FCSHP; Toronto, ON, Canada. J. Joel Jeffries; MB, FRCPC, DFCPA; Centre for Addiction and Mental Health and Department of Psychiatry, University of Toronto, Toronto, ON, Canada


Previous praise for the Clinical Handbook: As a psychiatrist who routinely prescribes medications, I find this handbook invaluable. It is the most comprehensive book on this topic that I have come across.; Corey Goldstein, MD, Rush University Medical Center; A powerhouse of practical information ...Unrivalled in scope ... This outstanding and unique handbook is as rich in useful content as many full textbooks.; Barbara Jovaisas, PharmD, in Canadian Pharmacists Journal.; Comprehensive ... clearly organized ... an ideal resource for rapid and straight-forward retrieval of essential clinical information ...a `must have' for those who work in mental health care.; Marshall Cates, PharmD, in Annals of Pharmacotherapy.; Should be available at all nursing stations.; C. Lindsay DeVane, PharmD, in American Journal of Health Systems Pharmacy.; The handbook is easy to use, comprehensive in scope, and up to date - a winner!; Catherine Chiles, MD, in the Journal of Clinical Psychiatry; "This is the new edition of a very important book that provides valuable information which otherwise would be scattered among different publications. With the increasing rate of prescription of psychotropic drugs, this volume should be on the desk of every physician. The information is crucial for understanding side effects, vulnerabilities, and interactions of psychotropic drug treatment."; Giovanni A. Fava, MD, in Psychotherapy and Psychosomatics, September 2019

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