Table of Contents

Preface; Acknowledgements; 1. Introduction to MR spectroscopy in vivo; 2. Pulse sequences and protocol design; 3. Spectral analysis methods, quantitation and common artifacts; 4. Normal regional variations: brain development and aging; 5. MRS in brain tumors; 6. MRS in stroke and hypoxic-ischemic encephalopathy; 7. MRS in infectious, inflammatory and demyelinating lesions; 8. MRS in epilepsy; 9. MRS in neurodegenerative disease; 10. MRS in traumatic brain injury; 11. Proton MR spectroscopy in brain metabolic disorders; 12. MRS in prostate cancer; 13. MRS in breast cancer; 14. MRS in musculoskeletal disease; Index.

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Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

About the Author

Peter B. Barker is Professor of Radiology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Nicola de Stefano is Associate Professor of Neurology, University of Siena, Siena, Italy. Alberto Bizzi is Neuroradiologist, Division of Neuroradiology, Fondazione, IRCCS Instituto Neurologico Besta, Milan, Italy. Rao Gullapalli is Associate Professor and Director, Core for Translational Research in Imaging at the University of Maryland, MD, USA. Doris D. M. Lin is Assistant Professor of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Reviews

'It is an excellent textbook for the initial foray into the topic and a great reference book … I would happily recommend [it] to anyone wanting to use MRS in clinical research and believe that it will encourage the use of this technology in mainstream practice.' The Lancet