Table of Contents

Cloning and expression of cytokine genes
Methods for studying cytokine gene polymorphisms
Northern analysis, RT-PCR, Rnase protection, cDNA array systems and in situ hybridization detection of cytokine messenger RNA
Purification, sequencing and synthesis of cytokines and chemokines
Receptor binding studies
Cytokine signalling
Cytokine receptor signalling pathways: PC-specific phospholipase C and sphingomyelinases
Proteome analysis in cytokine research
Conditional and fixed cytokine gene modification in transgenic and mutant mice