Table of Contents

ALTERATIONS OF THE DENDRITIC CELL SYSTEM IN CANCER.- The Central Role of Dendritic Cells in Immunity.- Dendritic Cells in Cancer: Emergenceof the Discipline.- Tumor-Infiltrating Dendritic Cells: The Pathologist’s Perspective.- Functional Defects of Dendritic Cells in Cancer.- General Properties of Dendritic Cell Populations in Cancer.- Elimination of Dendritic Cells in Cancer.- Mechanisms of Dendritic Cell Dysfunction in Cancer.- Tumor-Derived Factors Responsible for Dendritic Cell Dysfunction.- Tumor-Derived Exosomes as Dendritic Cell Modulators.- Signaling Pathways Mediating Dendritic Cell Dysfunction in Cancer.- A Role for STAT3 in Dendritic Cell Regulation by Tumor-Derived Factors.- Tumor-Associated Inflammation and Impact on Dendritic Cell Function.- Changes in Dendritic Cells in Cancer and Aging.- Stress, Immunity and Dendritic Cells in Cancer.- Cancer Therapy and Dendritic Cell Immunomodulation.- Role of Dendritic Cells in Tumor Escape.- Role of IDO in Dendritic Cell Differentiation and Function in Cancer.- Dendritic Cells: From Inducers of Specific T-Cell Responses to Promoters of Angiogenesis.- Protumorigenic Function of Dendritic Cells.- Dendritic Cell Maturation Versus Polarization in Tumor Escape.- Dendritic Cells in Cancer: Clinical Aspects.- Trafficking of Dendritic Cells in the Tumor Environment.- Dendritic Cells in Tumor-Draining Lymph Nodes.- Dendritic Cell Vaccines in Cancer: Obstaclesto Overcome.- How Best to Generate Dendritic Cells from Patients with Cancer and How Best to Use them for Immunotherapeutic Purposes.- Genetically Modified Dendritic Cells in Cancer Immunotherapy.- Dendritic Cell Tumors.- Future Directions in Dendritic Cell Research in Cancer.