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An invaluable resource that provides practical examples of actual formulations and outcomes in tablet design and manufacturing and offers real-world solutions to the associated major challenges.

Table of Contents

PrefaceAbbreviations

Chapter 1 Introduction

1.1 General Considerations1.2 Particle Sizes1.3 Excipients1.4 Mixing of Pharmaceutical Powders1.5 Statistical Methods1.6 Equipment

Chapter 2 Rapid Release Tablets

2.1 Low dose tablet by Direct Compression2.2 High Dose Tablet by Direct Compression2.3 Insoluble API, Low Dose Tablet by Wet Granulation2.4 Soluble API, Low Dose Tablet by Wet Granulation2.5 Insoluble API, High Dose Tablet by Wet Granulation2.6 Soluble API, High Dose Tablet by Wet Granulation

Chapter 3 Sustained Release (SR) Tablets

3.1 SR Tablet Using a Lipid Release Control Agent3.2 SR Tablet Using HPMC/Eudragit3.3 SR Tablet Using HPMC Mixtures

About the Author

Dr. Eyjolfsson entered pharmacy in 1959, having studied at the University of Iceland and then at the Pharmaceutical University of Denmark, Copenhagen 1961-1964 (MsPharm 1964). Dr. Eyjolfsson earned a Ph.D. in the chemistry of natural product from same university in 1968. He moved to Iceland in 1971 and has worked with drug formulation science at Pharmaco, Delta, Actavis until 2010. Dr. Eyjolfsson is an author of approximately 30 scientific papers in peer reviewed journals mainly on phytochemistry and pharmaceutics. He has designed many different dosage forms but mostly conventional tablets and slow release tablets.

Reviews

"...it would be of most benefit to persons with a solid grounding in the theory of pharmaceutical development who are starting to work in the area of solid dosage form design." --The Pharmaceutical Journal, January 2015