Table of Contents

Chapter 1 Origins of brain insulin and its function.- Chapter 2 Epidemiological evidence of the relationship between diabetes and dementia.- Chapter 3 Molecular pathophysiology of insulin depletion, mitochondrial dysfunction, and oxidative stress in Alzheimer’s Disease Brain.- Chapter 4 The Full Spectrum of Alzheimer's Disease is Rooted in Metabolic.- Derangements That Drive Type 3 Diabetes.- Chapter 5 The roles of apolipoprotein E, lipids and glucose in the pathogenesis of Alzheimer’s disease.- Chapter 6 Molecular connection between diabetes and dementia.- Chapter 7 Type II Diabetes mellitus accelerates age-dependent A pathology in cynomolgus monkey brain.- Chapter 8 Diabetes-related dementia.- Chapter 9 Tortuous paths of insulin signaling and mitochondria in Alzheimer's disease.- Chapter 10 Mammalian target of rapamycin at the crossroad between Alzheimer’s Disease and diabetes.- Chapter 11 Therapeutic strategies for Alzheimer’s disease in the view of diabetes mellitus.

About the Author

Dr. Yusaku NakabeppuMedical Institute of Bioregulation, Kyushu University, Japan
Dr. Toshiharu NinomiyaDept. of Epidemiology and Public Health, Grad. School of Med. Sci., Kyushu Univ., Japan