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Diagnostic Atlas of Renal Pathology


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Table of Contents

1. Approach to Diagnosis of the Kidney Biopsy 2. Normal Growth and Maturation 3. Glomerular Diseases PRIMARY GLOMERULAR DISEASES Glomerular Diseases That Cause Nephrotic Syndrome: Non-Immune Complex Glomerular Diseases That Cause Nephrotic/Nephritic Syndrome: Complement Related Glomerular Diseases That Cause Nephrotic Syndrome: Immune Complex Glomerular Diseases That Cause Hematuria or Nephritic Syndrome: Immune Complex SECONDARY GLOMERULAR DISEASES Diseases Associated with Nephrotic Syndrome Diseases Associated with Nephritic Syndrome or RPGN: Immune Mediated Diseases Associated with the Nephritic Syndrome or RPGN: Pauci-Immune- or Non-Immune-Mediated Diseases with Abnormal Basement Membranes Glomerular Involvement with Bacterial Infections 4. Vascular Diseases Diabetic Nephropathy Thrombotic Microangiopathy/ Thrombotic Thrombocytopenic Purpura Scleroderma Antiphospholipid Antibody Disease Preeclampsia and Eclampsia Fibromuscular Dysplasia Arterionephrosclerosis Accelerated/Malignant Hypertension Atheroemboli 5. Tubulointerstitial Diseases Introduction Infections of the Kidney Acute Pyelonephritis Chronic Pyelonephritis and Reflux Nephropathy Xanthogranulomatous Pyelonephritis Malakoplakia Acute Tubulointerstitial Nephritis - Viral Infection Acute Tubulointerstitial Nephritis-Drug-Related Tubulointerstitial Nephritis With Uveitis Anti-TBM Antibody Nephritis IgG4-Related Tubulointerstitial Nephritis Interstitial Nephritis of Sjogren Syndrome Sarcoidosis Acute Kidney Injury/Acute Tubular Necrosis Warfarin-Induced Acute Kidney Injury/ Anticoagulant- Related Nephropathy Heavy Metal Nephropathy (Lead and Cadmium Nephropathy) Analgesic Nephropathy and Papillary Necrosis Light Chain Cast Nephropathy and Tubulopathy Tubular Crystallopathies Lithium Nephropathy Aristolochic Acid Nephropathy 6. Endemic Nephropathies Introduction Aristolochic Acid Nephropathy Other Endemic Fibrosing Nephropathies 7. Chronic Kidney Disease Introduction Age-Related Sclerosis Glomerular vs. Tubulointerstitial vs. Vascular Disease Segmental Glomerulosclerosis: Primary vs. Secondary 8. Renal Transplantation Introduction Evaluation of Donor Kidneys Antibody-Mediated Rejection Chronic Active Antibody- Mediated Rejection and Transplant Glomerulopathy Acute T Cell-Mediated Rejection Chronic T Cell-Mediated Rejection Interstitial Fibrosis and Tubular Atrophy Cyclosporin/Tacrolimus Nephrotoxicity Sirolimus (Rapamycin) Nephrotoxicity Posttransplant Lymphoproliferative Disease Viral Infections Recurrent Renal Disease 9. Cystic Diseases of the Kidney Introduction Autosomal Dominant Polycystic Kidney Disease Autosomal Recessive Polycystic Kidney Disease Medullary Cystic Diseases Medullary Sponge Kidney Acquired Cystic Disease Cystic Renal Dysplasia 10. Renal Neoplasia Introduction Renal Neoplasms Nephroblastoma (Wilms Tumor) Renal Angiomyolipoma Urothelial (Transitional Cell) Carcinoma of the Renal Pelvis

About the Author

Professor Agnes Borge Fogo completed her medical and pathology training at Vanderbilt University, Nashville, TN, USA. Her main research interests are focused on progression of chronic kidney disease and crosstalk between tubules and glomeruli, funded by the NIH and other sources. An expert in the area of diagnostic renal pathology, she has published over 520 research articles and reviews, authored two textbooks of renal pathology and created an online Atlas of Renal Pathology with AJKD and NKF. She received the Robert G. Narins award from the ASN and the Roscoe R. Robinson award from the ISN for her contributions in teaching. She has been a councilor of the ISN, served as Chair of its Renal Pathology Committee, with focus on developing educational tools related to kidney biopsy interpretation. She started her 2 year term as the President of the ISN at the 2021 World Congress of Nephrology meeting. She has served as Associate Editor for American Journal of Pathology and The Journal of the American Society of Nephrology. She is currently Section Editor for Nephrology, Dialysis and Transplantation and Associate Editor for Laboratory Investigation and Kidney International. She is the John L. Shapiro Professor of Pathology, Microbiology and Immunology, Professor of Medicine and Pediatrics and director of the Renal/Electron Microscopy Laboratory, at Vanderbilt University Medical Center. Michael Kashgarian, MD is professor emeritus of and senior research scientist in pathology. He received his medical degree from Yale School of Medicine in 1958, completed his residency in pathology at the Yale-New Haven Medical Center in 1963, and completed a fellowship in laboratory medicine at Yale-New Haven Hospital in 1964. While on the Yale faculty he established a diagnostic renal pathology and electron microscopy laboratory that bears his name. He was also a pioneer in understanding the process of organ rejection. Although Kashgarian has retired, he continues to be active in the diagnosis of renal and cardiac biopsies.


"This atlas is more than a collection of images; it is a condensed textbook or manual of nephropathology. It has served well generations of clinical nephrologists and I predict that it will still be popular among clinicians and their trainees.. I do not know of any better short or introductory book in this field." Reviewed by Ivan Damjanov, MD (University of Kansas Medical Center) Doody's Score: 97, 5 Stars!

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