Chapter 1 Glomerular Diseases
NORMAL GROWTH AND MATURATION
PRIMARY GLOMERULAR DISEASES
Glomerular Diseases that Cause Nephrotic Syndrome: Non-Immune
Complex
Introduction
Minimal Change Disease
Focal Segmental Glomerulosclerosis
Collapsing Glomerulopathy
Tip Lesion Variant of FSGS
Cellular Variant of FSGS
Perihilar Variant of FSGS
Congenital Nephrotic Syndrome of Finnish Type
Diffuse Mesangial Sclerosis
Glomerular Diseases that Cause Nephrotic/Nephritic Syndrome:
Complement-Related
C1q Nephropathy
Dense Deposit Disease
C3 Glomerulopathies
Glomerular Diseases that Cause Nephrotic Syndrome: Immune
Complex
Membranous Nephropathy
Membranoproliferative Glomerulonephritis Type 1
Fibrillary Glomerulonephritis
Immunotactoid Glomerulopathy
Glomerular Diseasesthat Cause Hematuria or Nephritic Syndrome:
Immune Complex
Acute Post-infectious Glomerulonephritis
IgA Nephropathy
SECONDARY GLOMERULAR DISEASES
Diseases Associated with Nephrotic Syndrome
Monoclonal Immunoglobulin Deposition Disease
Proliferative Glomerulonephritis with Monoclonal Immunoglobulin
Deposition
HIV-associated Nephropathy
Sickle Cell Nephropathy
Fabry's Disease
Lipoprotein Glomerulopathy
Lecithin-Cholesterol Acyltransferase Deficiency
Hereditary FSGS
Diseases Associated with Nephritic Syndrome or RPGN:
Immune-Mediated
Lupus Nephritis, Mesangial and Proliferative Types
Henoch-Sch�nlein Purpura
Mixed Connective Tissue Disease
Mixed Cryoglobulinemic Glomerulonephritis
Anti-GBM-Antibody Mediated Glomerulonephritis
Diseases Associated with Nephritic Syndrome or RPGN: Pauci-Immune-
or Non-Immune-Mediated
Introduction
Granulomatosis with Polyangiitis (Wegener's)/Microscopic
Polyangiitis
Polyarteritis Nodosa
Churg-Strauss Syndrome
Diseases of the Basement Membrane
Alport Syndrome
Thin Basement Membrane Lesions
Nail-Patella Syndrome
Glomerular Involvement with Bacterial Infections
Subacute Bacterial Endocarditis Glomerulonephritis
Shunt Nephritis
Chapter 2 Vascular Diseases
Diabetic Nephropathy
Thrombotic Microangiopathy/Thrombotic Thrombocytopenic Purpura
Scleroderma (Progressive Systemic Sclerosis)
Anti-phospholipid Antibody Disease
Preeclampsia and Eclampsia
Fibromuscular Dysplasia
Arterionephrosclerosis
Accelerated/Malignant Hypertension
Atheroemboli
Chapter 3 Tubulointerstitial Diseases
Introduction
Acute Pyelonephritis
Chronic Pyelonephritis and Reflux Nephropathy
Xanthogranulomatous Pyelonephritis
Malakoplakia
Acute Tubulointerstitial Nephritis-Drug-Related
Acute Tubulointerstitial Nephritis--Viral Infection
Anti-Tubular Basement Membrane Antibody Nephritis
IgG4-Related Tubulointerstitial Nephritis
Sarcoidosis
Acute Kidney Injury/Acute Tubular Necrosis
Heavy Metal Nephropathy (Lead and Cadmium Nephropathy)
Analgesic Nephropathy and Papillary Necrosis
Light Chain Cast Nephropathy and Tubulopathy
Tubular Crystallopathies
Indinavir Nephropathy
Lithium Nephropathy
Aristolochic Acid Nephropathy
Chapter 4 Chronic Kidney Disease
Introduction
Age-Related Sclerosis
Glomerular vs. Tubulointerstitial vs. Vascular Disease
Segmental Glomerulosclerosis-Primary vs. Secondary
Chapter 5 Renal Transplantation
Introduction��
Antibody-Mediated Rejection��
Chronic Active Antibody-Mediated Rejection and Transplant
Glomerulopathy
Acute T-Cell-Mediated Rejection
Chronic Allograft Failure (Chronic Allograft Nephropathy)
Cyclosporin/FK506 Nephrotoxicity��
Post-Transplant Lymphoproliferative Disease��
Viral Infections��
Chapter 6 Cystic Diseases of the Kidney
Introduction��
Autosomal dominant polycystic kidney disease��
Autosomal recessive polycystic kidney disease��
Medullary cystic disease��
Medullary sponge kidney��
Acquired cystic disease��
Cystic renal dysplasia��
Chapter 7 Renal Neoplasia
Introduction��
Renal Cell Carcinomas��
Other Renal Epithelial Tumors��
Wilms' Tumor��
Transitional Cell Carcinoma of the Renal Pelvis��
Professor Agnes Borge Fogo completed her medical and pathology training at Vanderbilt University, Nashville, TN, USA. Her main research interests are focused on progression of chronic kidney disease and crosstalk between tubules and glomeruli, funded by the NIH and other sources. An expert in the area of diagnostic renal pathology, she has published over 520 research articles and reviews, authored two textbooks of renal pathology and created an online Atlas of Renal Pathology with AJKD and NKF. She received the Robert G. Narins award from the ASN and the Roscoe R. Robinson award from the ISN for her contributions in teaching. She has been a councilor of the ISN, served as Chair of its Renal Pathology Committee, with focus on developing educational tools related to kidney biopsy interpretation. She started her 2 year term as the President of the ISN at the 2021 World Congress of Nephrology meeting. She has served as Associate Editor for American Journal of Pathology and The Journal of the American Society of Nephrology. She is currently Section Editor for Nephrology, Dialysis and Transplantation and Associate Editor for Laboratory Investigation and Kidney International. She is the John L. Shapiro Professor of Pathology, Microbiology and Immunology, Professor of Medicine and Pediatrics and director of the Renal/Electron Microscopy Laboratory, at Vanderbilt University Medical Center. Michael Kashgarian, MD is professor emeritus of and senior research scientist in pathology. He received his medical degree from Yale School of Medicine in 1958, completed his residency in pathology at the Yale-New Haven Medical Center in 1963, and completed a fellowship in laboratory medicine at Yale-New Haven Hospital in 1964. While on the Yale faculty he established a diagnostic renal pathology and electron microscopy laboratory that bears his name. He was also a pioneer in understanding the process of organ rejection. Although Kashgarian has retired, he continues to be active in the diagnosis of renal and cardiac biopsies.
"It is essential for renal pathology fellows and residents in pathology. It also would be a great resource for renal pathologists and nephrologists." - Doody's Reviews, review of last edition "The book will be appreciated by anyone who is trying to get to grips with renal pathology, including both pathology and renal trainees. There are schematic representations of glomerular diseases, which are particularly useful for getting some key concepts across...Also new are boxes with key diagnostic features and summaries of differential diagnoses. these are a great asset, as in many textbooks the important points for clinical practice can be lost in the wealth of information provided....This atlas is an ideal reference book for a wide audience of reporting pathologists and renal physicians, both in training and as consultants. It presents renal pathology in a user-friendly and concise format, and it should help its user to shine at the renal multidisciplinary meeting, by using the differential diagnosis boxes to ask insightful and probing questions! It is also an excellent resource for the academic pathologists with teaching duties, in particular through the online content! (Expert Consult)"Royal College of Pathologist, Summer 2012 "The book successfully accomplishes the authors' goals. Along with other major books in the field, this atlas provides in-depth and detailed illustrations of a large spectrum of morphological lesions encountered in the renal biopsy and an approach to differential diagnosis and key prognostic, pathogenetic, and etiologic information. This edition will continue to be a widely used resource by medical students, pathologists, and clinicians."- Virgilius Cornea, MD (University of Kentucky College of Medicine) 4 star rating! Doody's Reviews
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