Table of Contents

Chapter 1 Glomerular Diseases NORMAL GROWTH AND MATURATION PRIMARY GLOMERULAR DISEASES Glomerular Diseases that Cause Nephrotic Syndrome: Non-Immune Complex Introduction Minimal Change Disease Focal Segmental Glomerulosclerosis Collapsing Glomerulopathy Tip Lesion Variant of FSGS Cellular Variant of FSGS Perihilar Variant of FSGS Congenital Nephrotic Syndrome of Finnish Type Diffuse Mesangial Sclerosis Glomerular Diseases that Cause Nephrotic/Nephritic Syndrome: Complement-Related C1q Nephropathy Dense Deposit Disease C3 Glomerulopathies Glomerular Diseases that Cause Nephrotic Syndrome: Immune Complex Membranous Nephropathy Membranoproliferative Glomerulonephritis Type 1 Fibrillary Glomerulonephritis Immunotactoid Glomerulopathy Glomerular Diseasesthat Cause Hematuria or Nephritic Syndrome: Immune Complex Acute Post-infectious Glomerulonephritis IgA Nephropathy SECONDARY GLOMERULAR DISEASES Diseases Associated with Nephrotic Syndrome Monoclonal Immunoglobulin Deposition Disease Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition HIV-associated Nephropathy Sickle Cell Nephropathy Fabry's Disease Lipoprotein Glomerulopathy Lecithin-Cholesterol Acyltransferase Deficiency Hereditary FSGS Diseases Associated with Nephritic Syndrome or RPGN: Immune-Mediated Lupus Nephritis, Mesangial and Proliferative Types Henoch-Sch nlein Purpura Mixed Connective Tissue Disease Mixed Cryoglobulinemic Glomerulonephritis Anti-GBM-Antibody Mediated Glomerulonephritis Diseases Associated with Nephritic Syndrome or RPGN: Pauci-Immune- or Non-Immune-Mediated Introduction Granulomatosis with Polyangiitis (Wegener's)/Microscopic Polyangiitis Polyarteritis Nodosa Churg-Strauss Syndrome Diseases of the Basement Membrane Alport Syndrome Thin Basement Membrane Lesions Nail-Patella Syndrome Glomerular Involvement with Bacterial Infections Subacute Bacterial Endocarditis Glomerulonephritis Shunt Nephritis Chapter 2 Vascular Diseases Diabetic Nephropathy Thrombotic Microangiopathy/Thrombotic Thrombocytopenic Purpura Scleroderma (Progressive Systemic Sclerosis) Anti-phospholipid Antibody Disease Preeclampsia and Eclampsia Fibromuscular Dysplasia Arterionephrosclerosis Accelerated/Malignant Hypertension Atheroemboli Chapter 3 Tubulointerstitial Diseases Introduction Acute Pyelonephritis Chronic Pyelonephritis and Reflux Nephropathy Xanthogranulomatous Pyelonephritis Malakoplakia Acute Tubulointerstitial Nephritis-Drug-Related Acute Tubulointerstitial Nephritis--Viral Infection Anti-Tubular Basement Membrane Antibody Nephritis IgG4-Related Tubulointerstitial Nephritis Sarcoidosis Acute Kidney Injury/Acute Tubular Necrosis Heavy Metal Nephropathy (Lead and Cadmium Nephropathy) Analgesic Nephropathy and Papillary Necrosis Light Chain Cast Nephropathy and Tubulopathy Tubular Crystallopathies Indinavir Nephropathy Lithium Nephropathy Aristolochic Acid Nephropathy Chapter 4 Chronic Kidney Disease Introduction Age-Related Sclerosis Glomerular vs. Tubulointerstitial vs. Vascular Disease Segmental Glomerulosclerosis-Primary vs. Secondary Chapter 5 Renal Transplantation Introduction Antibody-Mediated Rejection Chronic Active Antibody-Mediated Rejection and Transplant Glomerulopathy Acute T-Cell-Mediated Rejection Chronic Allograft Failure (Chronic Allograft Nephropathy) Cyclosporin/FK506 Nephrotoxicity Post-Transplant Lymphoproliferative Disease Viral Infections Chapter 6 Cystic Diseases of the Kidney Introduction Autosomal dominant polycystic kidney disease Autosomal recessive polycystic kidney disease Medullary cystic disease Medullary sponge kidney Acquired cystic disease Cystic renal dysplasia Chapter 7 Renal Neoplasia Introduction Renal Cell Carcinomas Other Renal Epithelial Tumors Wilms' Tumor Transitional Cell Carcinoma of the Renal Pelvis

About the Author

Dr. Agnes Fogo, M.D., F.A.S.N. serves as Member of Scientific Advisory Board of Angion Biomedica Corp. Dr. Fogo is the John L. Shapiro Chair of Pathology, Professor of Pathology, Medicine and Pediatrics and Director, Division of Renal Pathology and Electron Microscopy at Vanderbilt University Medical Center. An expert in the area of glomerulosclerosis, Dr. Fogo has published over 280 research articles and reviews and has authored two textbooks of renal pathology. She has served as Pathology Editor for the American Journal of Kidney Disease, Associate Editor for American Journal of Pathology and The Journal of the American Society of Nephrology. She is currently Section Editor for Nephrology Dialysis and Transplantation and Associate Editor for Laboratory Investigation. Michael Kashgarian, MD is professor emeritus of and senior research scientist in pathology. He received his medical degree from Yale School of Medicine in 1958, completed his residency in pathology at the Yale-New Haven Medical Center in 1963, and completed a fellowship in laboratory medicine at Yale-New Haven Hospital in 1964. While on the Yale faculty he established a diagnostic renal pathology and electron microscopy laboratory that bears his name. He was also a pioneer in understanding the process of organ rejection. Although Kashgarian has retired, he continues to be active in the diagnosis of renal and cardiac biopsies.

Reviews

It is essential for renal pathology fellows and residents in pathology. It also would be a great resource for renal pathologists and nephrologists. - Doody's Reviews, review of last edition

The book will be appreciated by anyone who is trying to get to grips with renal pathology, including both pathology and renal trainees. There are schematic representations of glomerular diseases, which are particularly useful for getting some key concepts across...Also new are boxes with key diagnostic features and summaries of differential diagnoses. these are a great asset, as in many textbooks the important points for clinical practice can be lost in the wealth of information provided....This atlas is an ideal reference book for a wide audience of reporting pathologists and renal physicians, both in training and as consultants. It presents renal pathology in a user-friendly and concise format, and it should help its user to shine at the renal multidisciplinary meeting, by using the differential diagnosis boxes to ask insightful and probing questions! It is also an excellent resource for the academic pathologists with teaching duties, in particular through the online content! (Expert Consult) Royal College of Pathologist, Summer 2012

The book successfully accomplishes the authors' goals. Along with other major books in the field, this atlas provides in-depth and detailed illustrations of a large spectrum of morphological lesions encountered in the renal biopsy and an approach to differential diagnosis and key prognostic, pathogenetic, and etiologic information. This edition will continue to be a widely used resource by medical students, pathologists, and clinicians.- Virgilius Cornea, MD (University of Kentucky College of Medicine) 4 star rating! Doody's Reviews