Preface; Part I. Introduction and Biological Databases: 1. Introduction; 2. Introduction to biological databases; Part II. Sequence Alignment: 3. Pairwise sequence alignment; 4. Database similarity search; 5. Multiple sequence alignment; 6. Profiles and hidden Markov models; 7. Protein motifs and patterns; Part III. Gene and Promoter Prediction: 8. Gene prediction; 9. Promoter and regulatory element prediction; Part IV. Molecular Phylogenetics: 10. Phylogenetics basics; 11. Phylogenetic tree construction methods and programs; Part V. Protein Structure Basics: 12. Protein structure basics; 13. Protein structure visualization, comparison and classification; 14. Protein secondary structure prediction; 15. Protein tertiary structure prediction; 16. RNA structure prediction; Part VI. Genomics and Proteomics: 17. Genome mapping, assembly and comparison; 18. Functional genomics; 19. Proteomics; Practical exercises; Glossary.
Clear, concise introduction to bioinformatics, written specifically to be accessible to a life science audience.
Jin Xiong is Assistant Professor of Biology at Texas A & M University, where he has taught bioinformatics to graduate and undergraduate students for several years.
'Essential Bioinformatics is a welcome addition to this area, by having a broad general approach that I think is particularly suitable for undergraduate teaching. The advantage of this being a new book is that there is not an overriding focus on structural bioinformatics that was seen in some earlier texts, which allows for a much broader coverage of newer areas like comparative and functional genomics.' http://www.sgm.ac.uk/pubs/micro_today/book_reviews/MTNOV06/MTN06_31.cfm 'The book would be ideal for biologists who wish to gain a grasp of the different analysis techniques available to the microarray user.' http://www.sgm.ac.uk/pubs/micro_today/book_reviews/MTAUG04/MTA04_13.cfm 'Awareness of bioinformatics is essential in a modern microbiological qualification and as this subject matures there are an increasing number of texts available. Essential Bioinformatics is a welcome addition to this area, by having a broad general approach that I think is particularly suitable for the undergraduate teaching.' Gavin Thomas, University of York