Table of Contents

1. INTRODUCTION          

2. BRIEF HISTORICAL NOTE         

2.1.A brief history of the cerebellum

2.2. The Contributions of Gordon Holmes and Olof Larsell                            

3. ANATOMY AND HISTOLOGY OF THE CEREBELLUM      

3.1 Gross anatomy of the cerebellum

3.2 Vascular supply and territories of the cerebellum

3.3 The olivocerebellar tract

3.4 Pre-cerebellar nuclei

3.5 Vestibular nuclei and their cerebellar connections

3.6 Spinocerebellar and cerebellospinal pathways

3.7 Visual circuits

3.8 Connectional anatomy of the cerebrocerebellar system        

3.9 Cerebello-cerebral feedback projections

4. EMBRYOLOGY AND DEVELOPMENT OF THE CEREBELLUM

4.1 Cerebellar neurogenesis

4.2 Zones and stripes

4.3 Specification of cerebellar neurons

4.4 Cerebellar nuclei development

4.5 Development of glutamatergic and GABAergic synapses

4.6 Synaptogenesis and synapse elimination in developing cerebellum

4.7 Cerebellar epigenetics: Transcription of microRNAs in Purkinje cells

5. CEREBELLAR CIRCUITS: BIOCHEMISTRY, NEUROTRANSMITTERS AND NEUROMODULATION

5.1. granule cells and parallel fibers

5.2. Purkinje neurons

5.3. Stellate cells

5.4. Basket cells

5.5. Golgi neurons

5.6. Lugaro cells

5.7. Unipolar brush cells

5.8. Glial cells

5.9. GABA pathways and receptors

5.10. Glutamatergic pathways and receptors

5.11. Norepinephrine

About the Author

International panel of editors: the 6 editors have a strong experience in research and/or in the clinic. They all devote most of their time to cerebellar research and have regular teaching duties for several of them. Through their networks, their students and the attendance to international conferences, they will contribute to a fast dissemination of the book.
International panel of authors: the book will gather an international panel of scientists who are key-players in the field. They are located in USA, in Europe and in Asia. Many of them have contributed to the Handbook and we also aim to attract novel authors or young talented scientists. The authors will come from the best clinical centers, universities or research centers in the world.