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1. INTRODUCTION 2. BRIEF HISTORICAL NOTE 2.1.A brief history of the
cerebellum2.2. The Contributions of Gordon Holmes and Olof Larsell
3. ANATOMY AND HISTOLOGY OF THE CEREBELLUM 3.1 Gross anatomy of
the cerebellum3.2 Vascular supply and territories of the
cerebellum3.3 The olivocerebellar tract3.4 Pre-cerebellar nuclei3.5
Vestibular nuclei and their cerebellar connections 3.6
Spinocerebellar and cerebellospinal pathways3.7 Visual circuits3.8
Connectional anatomy of the cerebrocerebellar system 3.9
Cerebello-cerebral feedback projections 4. EMBRYOLOGY AND
DEVELOPMENT OF THE CEREBELLUM 4.1 Cerebellar neurogenesis4.2 Zones
and stripes4.3 Specification of cerebellar neurons4.4 Cerebellar
nuclei development4.5 Development of glutamatergic and GABAergic
synapses4.6 Synaptogenesis and synapse elimination in developing
cerebellum4.7 Cerebellar epigenetics: Transcription of microRNAs in
Purkinje cells 5. CEREBELLAR CIRCUITS: BIOCHEMISTRY,
NEUROTRANSMITTERS AND NEUROMODULATION 5.1. granule cells and
parallel fibers5.2. Purkinje neurons5.3. Stellate cells5.4. Basket
cells5.5. Golgi neurons5.6. Lugaro cells5.7. Unipolar brush
cells5.8. Glial cells5.9. GABA pathways and receptors5.10.
Glutamatergic pathways and receptors5.11. Norepinephrine<5.12.
Serotonin5.13. Nitric oxide5.14. Cannabinoids5.15. Purinergic
signaling5.16. Neuropeptides5.17. Neurosteroids5.18. Cerebellar
networks
5.19. Distributed Plasticity
6. BASIC PHYSIOLOGY 6.1. Oscillation in the Inferior Olive
neurons: Functional Implication6.2. Simple spikes and complex
spikes6.3. Rebound Depolarization and Potentiation6.4. Cerebellar
Nuclei6.5. Plasticity of cerebellum6.6. Physiology of
Olivo-Cerebellar Loops6.7. Long-term depression at parallel
fiber-Purkinje cell synapses6.8. Regulation of Calcium in the
Cerebellum 7. NEUROIMAGING OF THE CEREBELLUM 7.1.Cerebellar closed
loops7.2.MRI aspects7.3.SPECT and PET7.4.Spectroscopy7.5.Functional
topography 8.FUNCTIONAL PROPERTIES OF THE CEREBELLUM
8.1.Cerebrocerebellar networks8.2.Clinical functional topography in
cognition 8.3. Sequencing8.4. Speech and language 9.CELLULAR AND
ANIMAL MODELS OF CEREBELLAR DISORDERS 9.1 The zebrafish
cerebellum9.2 The teleost fish9.3 Lurcher mouse9.4 The tottering
mouse9.5 The rolling Nagoya mouse9.6 The ataxic Syrian hamster9.7
Lesions of the cerebellum9.8 Staggerer mouse 10.HUMAN CEREBELLAR
SYMPTOMS: FROM MOVEMENT TO COGNITION 10.1.Oculomotor
disorders10.2.Speech deficits10.3.Deficits of limb
movements10.4.Lesion-symptom mapping10.5.The cerebellar cognitive
affective syndrome10.6.Clinical scales of ataxias 11.HUMAN
CEREBELLAR DISORDERS: FROM PRENATAL PERIOD TO ELDERLY
11.1.Differential diagnosis based on age11.2.Pediatric ataxias -
Overview11.3.Autism spectrum disorders11.4.Autosomal recessive
ataxias11.5.X-linked ataxias11.6.Imaging of cerebellar
malformations11.7.Cerebellar stroke11.8.Immune
diseases11.9.Paraneoplastic ataxias11.10.Essential
tremor11.11.Toxic agents11.12. Endocrine disorders 12.THERAPIES OF
CEREBELLAR ATAXIAS 12.1.Drugs in selected
ataxias12.2.Cerebellostimulation12.3.RehabilitationINDEX
International panel of editors: the 6 editors have a strong
experience in research and/or in the clinic. They all devote most
of their time to cerebellar research and have regular teaching
duties for several of them. Through their networks, their students
and the attendance to international conferences, they will
contribute to a fast dissemination of the book.
International panel of authors: the book will gather an
international panel of scientists who are key-players in the field.
They are located in USA, in Europe and in Asia. Many of them have
contributed to the Handbook and we also aim to attract novel
authors or young talented scientists. The authors will come from
the best clinical centers, universities or research centers in the
world.
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