TABLE OF CONTENT
1. The extracellular matrix goes - omics: resources and tools.
2.The matrisome of model organisms: from in-silico prediction
to big-data annotation
3.Detecting changes to the extracellular matrix in liver
diseases
4. Characterization of Proteoglycanomes by Mass Spectrometry
5. Historical overview of integrated GAG-omics and proteomics
6.Extracellular matrix networks: from connections to functions
7. Integration of Matrisome Omics: Towards System Biology of the Tumor Matrisome
8. Proteomic and degradomic analysis of body fluids: applications, challenges and considerations
9. Regulation of Cell-Matrix Adhesion Networks: Insights from Proteomics
10. Integrative models for TGF- signaling and extracellular
matrix
Sylvie Ricard-Blum is Professor of Biochemistry at
the University of Lyon (France). She studies the structure,
interactions and functions of the extracellular matrix (ECM) using
biochemistry, biophysics, bioinformatics and systems biology. Her
laboratory has developed a roadmap and tools to build and
contextualize ECM interaction networks, including the database
MatrixDB. She has identified several hundreds of ECM interactions,
and built interaction networks of ECM proteins, bioactive ECM
fragments (matricryptins), glycosaminoglycans and proteoglycans
leading to the prediction of new functions for a number of them.
Her current research aims at determining the role of intrinsic
disorder, cross-linking, proteolysis and mutations in rewiring ECM
networks in disease with a focus on matricryptins, lysyl oxidases
and syndecans. She has been Secretary and President of the French
Society for Matrix Biology, and serves as Associate Editor of
Matrix Biology and Matrix Biology Plus, Editor of the
newsletter of the International Society for Matrix Biology, and as
President of the International Society for Matrix Biology
(2019-2020).
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