Promotional Information

The most current and comprehensive review of GABAergic function in the basal ganglia.

Table of Contents

I. FUNDAMENTALS OF GABA IN THE BASAL GANGLIA
Basal Ganglia Macrocircuits.
GABA: Homeostatic and pharmacological aspects.
GABAA receptors: structure and function in the basal ganglia.
GABAB receptors: structure and function.
The cellular, molecular and ionic basis of GABAA receptor signalling.

II. GABAERGIC MICROCIRCUITS OF THE BASAL GANGLIA
GABAergic inhibition in the neostriatum.
Globus Pallidus external segment.
Globus pallidus internal segment.
The pars reticulata of the substantia nigra: a window to basal ganglia output.
GABAergic control of the subthalamic nucleus.
GABAergic control of substantia nigra dopaminergic neurons.
GABAergic output of the basal ganglia.

III. GABAERGIC NEUROTRANSMISSION IN THE BASL GANGLIA
Localization of GABA receptors in the basal ganglia.
Presynaptic modulation of GABA release in the basal ganglia.
Development of striatal fast-spiking GABAergic interneurons.
Co-localization of GABA with other neuroactive substances in the basal ganglia.

IV. SYSTEMS LEVEL ASPECTS OF GABA IN THE BASAL GANGLIA
GABAerigc circuits in the basal ganglia and movement disorders.
Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglie function.

V. EPILOGUE