Table of Contents

Foreword
Preface
List of Contributors
Glossary
Chapter 1. Getting Ready for Gene-Based Medicine
Chapter 2. Genomic Medicine – A Primer
Chapter 3. Genetic Testing
Chapter 4. Population Screening in the Age of Genomic Medicine
Chapter 5. Inheritance and Drug Response
Chapter 6. Pharmacogenomics – Drug Disposition, Drug Targets, and Side Effects
Chapter 7. Pharmacogenetics in the Laboratory and the Clinic
Chapter 8. Hereditary Colorectal Cancer
Chapter 9. Alzheimer's Disease and Parkinson's Disease
Chapter 10. Molecular Diagnosis of the Hematologic Cancers
Chapter 11. Breast and Ovarian Cancer
Chapter 12. Cardiovascular Disease
Chapter 13. Ethical, Legal, and Social Implications of Genomic Medicine
Chapter 14. Genomics as a Probe for Disease Biology
Chapter 15. Welcome to the Genomic Era
Index

About the Author

Francis S. Collins, M.D., Ph.D., is director of the National Human Genome Research Institute (NHGRI) at the National Institutes of Health. He shepherded the Human Genome Project to completion in 2003. Alan E. Guttmacher, M.D., is deputy director of the NHGRI and director of its Office of Policy, Communication, and Education. Jeffrey M. Drazen, M.D., is Editor-in-Chief of the New England Journal of Medicine.

Reviews

An indispensable guide to the full potential of the DNA-based transformation of medicine. Human Reproduction and Genetic Ethics The editors have assembled a fine set of short, readable and highly authoritative articles by eminent authors. The book is beautifully produced and will give an accessible entry into genetic medicine to its target audience of non-specialist clinicians. Readers of this journal will need no persuading of the fascination and ever growing importance of genetic medicine and these themes are well communicated. -- Andrew P. Read Human Genetics