Table of Contents

1. Historical Principles and Perspectives Paul M. Wax 2. Toxicologic Misfortunes and Catastrophes in History Paul M. Wax PART ATHE GENERAL APPROACH TO THE PATIENT 3. Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman 4. Principles of Managing the Acutely Poisoned or Overdosed Patient Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Lewis R. Goldfrank and Robert S. Hoffman [include eCPR, critical care dispositions] SC1. Principles of Antidote Stocking [Insert author(s)] 5. Decontamination Principles: Prevention of Gastrointestinal Absorption Lotte C. G. Hoegberg and Anne-Bolette Gude SC2. Decontamination Principles: Prevention of Dermal, Inhalational and Ocular Absorption [Insert author(s)] A1. Activated Charcoal Silas W. Smith and Mary Ann Howland A2. Whole-Bowel Irrigation and Other Intestinal Evacuants Silas W. Smith and Mary Ann Howland 6. Principles and Techniques Applied to Enhance Elimination David S. Goldfarb and Marc Ghannoum 7. Laboratory Principles Petrie M. Rainey 8. Principles of Diagnostic Imaging David T. Schwartz 9. Pharmacokinetic and Toxicokinetic Principles Mary Ann Howland PART BTHE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY SECTION I BIOCHEMICAL AND MOLECULAR CONCEPTS 10. Chemical Principles Stephen J. Traub and Lewis S. Nelson 11. Biochemical and Metabolic Principles Kurt C. Kleinschmidt and Kathleen A. Delaney 12. Fluid, Electrolyte, and Acid-Base Principles Alan N. Charney and Robert S. Hoffman 13. Neurotransmitters and Neuromodulators Steven C. Curry, Ayrn D. O'Connor, Kimberlie A. Graeme, Kirk C. Mills, and Aaron B. Skolnik 14. Withdrawal Principles Richard J. Hamilton and [new author] SECTION IIPATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS 15. Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles Cathleen Clancy 16. Cardiologic Principles II: Hemodynamics[new author] and Robert A. Hessler 17. Dermatologic Principles Jesse M. Lewin, Neal A. Lewin, and Lewis S. Nelson SC3. Transdermal ToxicologyLewis S. Nelson 18. Gastrointestinal Principles Matthew D. Zuckerman and Richard J. Church 19. Genitourinary Principles Jason Chu 20. Hematologic Principles Marco L.A. Sivilotti 21. Hepatic Principles Kathleen A. Delaney 22. Neurologic Principles Rama B. Rao 23. Oncologic PrinciplesRichard Wang 24. Ophthalmic Principles Adhi Sharma 25. Otolaryngologic Principles[new author] and William Chiang 26. Psychiatric Principles Erin A. Zerbo and Andrea M. Kondracke

About the Author

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide Mary Ann Howland, PharmD, DABAT, FAACT Clinical Professor of Pharmacy, St. John's University College of Pharmacy; Consultant, Department of Emergency Medicine, Bellevue Hospital Center and New York University Medical Center; Senior Consultant in Residence, New York City Poison Center, New York, New York. McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide