1. Introduction
Part I Methods for Quantifying Vascular Deformations2. Deciding
What You Need and How to Get It3. Medical Imaging Modalities and
Protocols4. Geometric Modeling5. Centerline Deformation Metrics6.
Surface Deformation Metrics
Part II Deformations of Vascular Beds Relevant for Medical
Devices7. Coronary Blood Vessels8. Neurovascular Blood Vessels9.
Thoracic Aorta and Arch Branches10. Abdominal Aorta and Visceral
Arteries11. Lower Extremity Arteries12. Inferior Vena Cava and
Lower Extremity Veins13. Upper Extremity Blood Vessels
Part III Developing and Utilizing Boundary Conditions14. Developing
Boundary Conditions for Durability Evaluation15. Summary of
Durability Evaluation Methods16. How to Improve Durability in a
Pinch17. Areas of Future Research18. Conclusions
Dr. Christopher Cheng has over 20 years of experience in academic research and the medical device industry. His academic research has focused on hemodynamics and vascular structure mechanics, with an emphasis on disease research and medical device interactions with the body. He has authored over 80 journal, conference, and book chapter publications. In his industry experience, Dr. Cheng has worked at small and large medical device companies, with experience spanning design, manufacturing, preclinical testing, clinical trials, and marketing. Currently, Dr. Cheng is CEO of Koli, Inc., an early-stage medical device company developing a catheter-based solution for gallstone disease. Dr. Cheng is also an Adjunct Professor in the Division of Vascular Surgery at Stanford, where he runs the Vascular Intervention Biomechanics & Engineering (VIBE) lab. Dr. Cheng earned his undergraduate degree in Biomedical Engineering and Electrical & Computer Engineering at Duke University. He then earned Master’s and Ph.D. degrees in Biomechanics at Stanford University.
"It’s exciting when a new field opens up -- and that’s where we are
with vascular motion. Dr. Cheng has provided a clear and highly
readable overview of the medical and engineering science
surrounding the motion of vessels and the consequences for
treatments and technologies. As a bonus, the book is sprinkled with
some intriguing hints of new things to come as clinicians,
investigators, and inventors pursue this rapidly evolving area."
--Paul G. Yock – Interventional Cardiologist, Martha Meier Weiland
Professor of Medicine, Professor of Bioengineering and Mechanical
Engineering (by courtesy), & Director of Byers Center for
Biodesign, Stanford University, Stanford, CA
"This first of its kind textbook deals with topics that will gain
increasing importance as endovascular grafts are increasingly used
to treat vascular lesions. These endografts have to dwell and
function in a hostile vascular environment governed by some of the
forces described in this unique text. Overcoming these forces is a
key challenge for the future. This book will help meet that
challenge." --Frank J. Veith – Vascular Surgeon, Professor of
Surgery, New York University, New York, NY and Director of
VEITHsymposium
"Handbook of Vascular Motion is destined to be a ‘must-read’ for
all those interested in the human vascular system. From anatomists
to physiologists, vascular clinicians to sports medicine
practitioners, biomedical engineers to medical device
entrepreneurs, all will find that this special volume provides
enlightening evidence of how data-driven insights have dramatically
enhanced our understanding of vascular motion and its impact on
normal function, development of vascular disease, and design of
durable vascular implants. Indeed, Professor Cheng's superb text
tackles a previously unaddressed need in an increasingly relevant
field of study by focusing on how motion in a wide range of
vascular beds impacts the design and performance of medical
devices. It is the first comprehensive source to provide a
well-organized presentation of the important considerations,
including previously unpublished scientific and computational data
that underpin the influential effects of vascular motion in
humans." --Michael D. Dake – Interventional Radiologist, Senior
Vice President of University of Arizona Health Sciences & Professor
of Medical Imaging, Surgery, and Medicine, University of Arizona,
Tuscon, AZ
"I very much enjoyed reading this book which provides a wealth of
information on the complex and dynamic movement of blood vessels
and how this motion can affect the effectiveness and durability of
intravascular devices used to treat cardiovascular disease. We have
witnessed remarkable advances in the sophistication and
effectiveness of implanted medical devices used to treat
cardiovascular disease, which is the number one cause of death and
disability in the world. However, our understanding of the
biomechanical forces acting on these devices as a result of the
complex, dynamic movement of blood vessels in everyday life is
limited. This is the first book to bring together the large body of
scientific information on the movement of blood vessels to show how
this motion can impact the durability and function of implanted
devices. This book is a must read and reference source for
physicians, scientists, biomedical engineers, medical device
developers, safety engineers, and regulators who have an interest
in improving the treatment of cardiovascular disease."
--Christopher K. Zarins – Vascular Surgeon, Emeritus Professor of
Surgery, Stanford University, Stanford, CA & Co-Founder and Senior
VP of Medical Affairs, HeartFlow, Inc., Redwood City, CA
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