Table of Contents

Important Biological Features
Introduction
Stocks and Strains
Nomenclature
Behavior
Anatomic and Physiologic Features
Normative Values
Hematology
Immunodeficient Mice
Wild Mice
References

Husbandry
Housing
Barriers and Containment
Personal Protective Equipment (PPE)
Special Considerations for Immunodeficient Mice
Environment
Sanitation and Pest Control
Nutrition
Water
Breeding
Identification and Record Keeping
Transportation
References

Management
Regulatory Agencies and Compliance
Institutional Animal Care and Use Committee (IACUC)
Occupational Health and Zoonotic Diseases
References

Clinical Medicine
Basic Veterinary Supplies
Physical Examination of the Mouse
Common Spontaneous and Noninfectious Diseases
Common Infectious Diseases
Treatment and Supportive Care of Sick Mice
Clinical Endpoints
Treating Disease on a Colony Basis
References

Preventive Medicine
Receiving
Testing of Biological Materials
Health Surveillance and Monitoring
Disease Prevention through Sanitation
References

Experimental Methodology
Restraint
Sampling Methods
Compound Administration
Phenotyping
Anesthesia and Analgesia
Euthanasia
Necropsy
References

Resources and Additional Information
Organizations
Publications
Electronic Resources

Appendix A: Glossary of Phenotyping Terminology and Tests
Appendix B: Suggested Cassette Numbering System and Some Trimming Suggestions
Index

About the Author

Peggy J. Danneman is a Senior Director of Laboratory Animal Health Services at The Jackson Laboratory in Bar Harbor, Maine. Mark A. Suekow is the Director of the Freimann Life Sciences Center at the University of Notre Dame, Indiana. Cory Brayton is the Director of Phenotyping Core for Johns Hopkins Medicine, Maryland.

Reviews

"This latest in-color edition includes new discussions on disease prevention and testing, transportation, and phenotyping... Overall, this book is well-written and highly applicable to today's laboratory animal care and use programs ... Like the first edition, it is a 'must have' for any reference library."

-Robin Crisler-Roberts, DVM, MS, DACLAM, Indiana University School of Medicine, Indianapolis, USA