Table of Contents

Chapter 1: Body Fluid Compartments and Intravenous Fluid Replacement, Robert F. Reilly, Jr., and Mark A. Perazella 1. Body fluid compartments
2. Intravenous solutions
3. General principles
4. Assessing extracellular fluid volume
5. Fluid resuscitation
6. Clinical examples of fluid resuscitation Chapter 2: Disorders of Sodium Balance (Edema, Hypertension or Hypotension), Robert F. Reilly, Jr., and Mark A. Perazella 1. Introduction
2. Regulation of Na+ transport in kidney
3. Disorders associated with increased total body Na+ (ECF volume expansion)
4. Clinical manifestations of increased total body Na+ (ECF volume expansion)
5. General approach to the edematous patient
6. General treatment of the edematous patient
7. Clinical manifestations of decreased total body Na+ (ECF volume depletion)
8. General approach to the volume depleted patient
9. General Treatment of the Volume Depleted Patient Chapter 3: Disorders of Water Balance (Hypo- and Hypernatremia), Robert F. Reilly, Jr., and Mark A. Perazella 1. Introduction
2. Hyponatremia
3. Etiology of hyponatremia
4. Signs and symptoms
5. Diagnosis
6. Treatment
7. Hypernatremia
8. Etiology
9. Signs and symptoms
10. Diagnosis
11. Treatment Chapter 4: Diuretics, Mark A. Perazella 1. Introduction
2. Sites of diuretic action in kidney
3. Diuretic resistance
4. Clinical conditions associated with diuretic resistance
5. Treatment of diuretic resistance Chapter 5: Disorders of K+ balance (Hypo- and Hyperkalemia), Mark A. Perazella 1. Introduction
2. K+ homeostasis
3. Role of K+ in the resting membrane potential
4. Cellular K+ distribution
5. K+ handling by the kidney
6. Factors controlling renal K+ excretion
7. Hypokalemia8. Etiology
9. Increased cellular K+ uptake
10. Increased renal K+ losses
11. Approach to the patient
12. Clinical manifestations
13. Treatment
14. Hyperkalemia
15. Etiology
16. Approach to the patient
17. Clinical manifestations
18. Treatment Chapter 6: Metabolic Acidosis, Dinkar Kaw and Joseph I. Shapiro 1. Acid-Base Chemistry and Biology
2. The Bicarbonate Buffering System
3. Acid Excretion by the Kidney
4. Clinical Approach to the Patient with an Acid-Base Disorder
5. Pathophysiology, Compensation and Consequences
6. Use of the Serum and Urine Anion Gap in the Differential Diagnosis of Metabolic Acidosis
7. Differential Diagnosis of Metabolic Acidosis
8. Causes of Metabolic Acidosis
9. Treatment of Metabolic Acidosis Chapter 7: Metabolic Alkalosis, Dinkar Kaw and Joseph I. Shapiro 1. Introduction
2. Maintenance of Metabolic Alkalosis
3. Clinical Features
4. Differential Diagnosis
5. Cl--Responsive and Cl--Resistant Causes of Metabolic Alkalosis
6. Treatment Chapter 8: Respiratory and Mixed Acid-base Disturbances, Youngsook Yoon and Joseph I. Shapiro 1. Respiratory Disturbances
2. Respiratory Acidosis
3. Respiratory Alkalosis
4. Mixed Disturbances Chapter 9: Disorders of Serum Calcium, Robert F. Reilly, Jr. 1. Regulation
2. Hypercalcemia
3. Hypocalcemia Chapter 10: Disorders of Serum Phosphorus, Robert F. Reilly, Jr. 1. Regulation
2. Hyperphosphatemia
3. Hypophosphatemia Chapter 11: Disorders of Serum Magnesium, Robert F. Reilly, Jr. 1. Introduction
2. Hypomagnesemia
3. Hypermagnesemia Chapter 12: Appendix, Mark A. Perazella and Robert F. Reilly, Jr. 1. Introduction
2. Clinical assessment of glomerular filtration rate (GFR)

About the Author

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide Mark Perazella, MD Associate Professor of Medicine Director, Clinical Nephrology Fellowship Program Yale University School of Medicine New Haven, CT