Table of Contents

Overview: What is gene expression?.- The impact of chromatin.- The basal transcriptional machinery.- Transcription factors.- Linking signal transduction and gene regulation.- Switching genes on and off at the example of nuclear receptors.- Mapping the genome.- Chromatin modifiers.- Genomic imprinting.- The epigenome.- Chromatin remodeling.- Chromatin architecture.- Regulatory RNA.

About the Author

Prof. Carsten Carlberg: Professor for biochemistry at the School of Medicine, Institute of Biomedicine at the University of Eastern Finland. The main research interests of Prof. Carlberg are (epi)genomics of nuclear receptors and their ligands with special focus on vitamin D. So far he published more than 190 papers (H-index 50). Since 2003 he is lecturing yearly the course "Nutrigenomics", which is the basis of this textbook. Together with Dr. Molnár he also published the Springer textbook "Mechanisms of gene regulation".

Dr. Ferdinand Molnár: Senior researcher at the School of Pharmacy, Institute of Biopharmacy, University of Eastern Finland. The main research interests of Dr. Molnár are the molecular structure of nuclear receptor proteins and their natural and synthetic ligands, on which he published more than 20 papers (H-index 14). Together with Prof. Carlberg he published the Springer textbook "Mechanisms of gene regulation".