Table of Contents

Section I: Population HealthChapter 1: Populationsa. Communityb. Regionc. Countryd. Globale. Special populationsChapter 2: Metricsa. Prevalenceb. Incidence ratec. Mortality rated. Infant mortalitye. Life expectancyf. Years of potential life lostg. Disability-adjusted life yearsChapter 3: Patterns of Occurrencea. Ageb. Race/ethnicityc. Genderd. Geographice. TemporalChapter 4: Global Burden of Diseasea. Study design and goalsb. Mortality patternsc. Healthy life expectancyd. Disability-adjusted life yearse. Risk factorsChapter 5: Social Determinants of Healtha. Definitionb. Whitehall Studyc. Educationd. Incomee. Housingf. Food securityg. Physical and social environmentChapter 6: Health Disparitiesa. Health Inequitiesb. Social determinantsc. Cultured. Discriminatione. Access to caref. Quality of careSection II. Collecting Evidence for Medical PracticeChapter 7: Clinical trialsa. Designb. Subject selectionc. Randomizationd. Blindinge. Analysisf. Sample sizeg. LimitationsChapter 8: Cohort studiesa. Designb. Subject selectionc. Exposure assessmentd. Analysise. LimitationsChapter 9: Case-control studiesa. Designb. Subject selectionc. Matchingd. Exposure assessmente. Analysisf. LimitationsChapter 10: Diagnostic testsa. Sensitivity and specificityb. Positive and negative predictive valuec. Likelihood ratiosd. ROC Curvese. LimitationsSection III. Assessing Evidence for Medical PracticeChapter 11: Comparative effectivenessa. Definitionb. Objectivesc. Approachesd. Systematic reviewse. PICOTS principlesChapter 12: Planning a reviewa. Selecting a topicb. Key informantsc. Analytic frameworkChapter 13: Finding evidencea. Study eligibilityb. Types of studiesc. Grey literatured. Possible biase. Search processf. Extracting datag. Reporting methodsChapter 14: Assessing the evidencea. Data extractionb. Study qualityc. Study applicabilityd. Summary tablee. Evidence MapsChapter 15: Quantitative synthesisa. Summary measuresb. Heterogeneous resultsc. Subgroup analysisd. Grading strength of evidencee. Reporting resultsSection IV: Translating Evidence into Medical Practice

About the Author

Raymond S. Greenberg, MD, PhD President Medical University of South Carolina Charleston, South Carolina Stephen R. Daniels, MD, PhD Professor University of Cincinnati School of Medicine Cincinnati, Ohio W. Dana Flanders, MD, DSc Professor Rollins School of Public Health Emory University Atlanta, Georgia John William Eley, MD, MPH Associate Professor Rollins School of Public Health Emory University Atlanta, Georgia John R. Boring, III, PhD Department of Epidemiology and Biostatistics Rollins School of Public Health Emory University Atlanta, Georgia