Table of Contents

About the editors

List of contributors

From the series editor

Introduction to the Classic Edition

Part I

Introduction

HOLLY A. TUOKKO AND IAN MCDOWELL

Part II

General Population Research on MCI

2 The PAQUID study

COLETTE FABRIGOULE, PASCALE BARBERGER-GATEAU, AND JEAN-FRANÇOIS DARTIGUES

3 Cognitive impairment in elderly persons without dementia: Findings from the Kungsholmen Project

KATIE PALMER, LARS BACKMAN, BRENT J. SMALL, AND LAURA FRATIGLIONI

4 Population levels of mild cognitive impairment in England and Wales

JANE FLEMING, FIONA E. MATTHEWS, MARK CHATFIELD, AND CAROL BRAYNE

5 The Melbourne Aging Study

ALEXANDER COLLIE, PAUL MARUFF, DAVID G. DARBY, COLIN MASTERS, AND JON CURRIE

Part III

Specific Samples

6 Mild cognitive impairment in the Religious Orders Study

7 A perspective from the Mayo Clinic

8 Prediction of probable Alzheimer's disease: The Sunnybrook Memory Study

9 Studies in the Leipzig Memory Clinic: Contribution to the concept of mild cognitive impairment

10 Emerging pharmacological therapies for mild cognitive impairment

12 Combined therapies in mild cognitive impairment

13 The future of mild cognitive impairment

HOLLY A. TUOKKO AND DAVID F. HULTSCH

Author index

Subject index

About the Author

Holly A. Tuokko was a Professor in the Department of Psychology and Institute on Aging and Lifelong Health at the University of Victoria. She was awarded Senior Investigator status through the Canadian Institutes of Health Research, Institute of Aging (2002–2007), for her program of research on mental health and aging.

David F. Hultsch was a Professor of Psychology at the University of Victoria from 1984 onward, with a major research focus on cognition and aging. He was a founder of the journal Aging, Neuropsychology, and Cognition, serving as co-editor for 10 years.

Reviews

"This valuable volume brings the kind of broad perspective to mild cognitive impairment that has long been needed. Rather than basing conclusions on a single sample or framework, the editors have pulled together articles from leading research groups around the world. This is the kind of comprehensive approach that is needed for developing systematic and valid definitions of MCI and identifying better tools that make it possible to differentiate between benign memory changes in later life and the early signs of pathological processes." - Steven H. Zarit, Department of Human Development and Family Studies, The Pennsylvania State University, USA."This volume provides the most comprehensive overview of mild cognitive impairment currently available. The conceptual and methodological challenges for studying MCI are tackled with rigor, and the complexities of defining the syndrome are not underestimated. This book is certain to become a classic text for those studying or researching cognitive agin, MCI and dementia, and for clinicians seeking an authoritative reference on the clinical manifestations of MCI." - Kaarin J. Anstey, Centre for Mental Health Research, Australian National University, Australia. "The editors of this book have done a great job. The description of the issues is laid out in a well-written introduction, making the descriptions of the research papers very accessible, even to the less well-informed reader. The conclusion likewise pulled together the various strands, including defining what still needs to be done to further refine the concept of MCI." - Graham A. Jackson, Laverndale Hospital, Scotland. In Dementia, August, 2008.

"This valuable volume brings the kind of broad perspective to mild cognitive impairment that has long been needed. Rather than basing conclusions on a single sample or framework, the editors have pulled together articles from leading research groups around the world. This is the kind of comprehensive approach that is needed for developing systematic and valid definitions of MCI and identifying better tools that make it possible to differentiate between benign memory changes in later life and the early signs of pathological processes." - Steven H. Zarit, Department of Human Development and Family Studies, The Pennsylvania State University, USA"This volume provides the most comprehensive overview of mild cognitive impairment currently available. The conceptual and methodological challenges for studying MCI are tackled with rigor, and the complexities of defining the syndrome are not underestimated. This book is certain to become a classic text for those studying or researching cognitive agin, MCI and dementia, and for clinicians seeking an authoritative reference on the clinical manifestations of MCI." - Kaarin J. Anstey, Centre for Mental Health Research, Australian National University, Australia"The editors of this book have done a great job. The description of the issues is laid out in a well-written introduction, making the descriptions of the research papers very accessible, even to the less well-informed reader. The conclusion likewise pulled together the various strands, including defining what still needs to be done to further refine the concept of MCI." - Graham A. Jackson, Laverndale Hospital, Scotland. In Dementia, August, 2008