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Mitochondria in Health and Disease


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Table of Contents

Part 1: Mitochondrial Functions. 1: What Are Mitochondria?. 2: Enabling Evolution. 3: Energy Production. 4: Mitochondrial Dynamics. 5: Maintaining Allostasis. 6: Acetyl-CoA: A vital energy source and controller of a cell. 7: Synthesising Cellular Components. 8: Ketone Metabolism. 9: Altering Immune Function. 10: Creating Short Bursts of Rapid Energy. 11: Calcium Storage and Regulation. 12: Apoptosis. 13: Haeme Production. 14: Supporting Kidney Detoxification. 15: Health, Toxicity and Hormesis. Part 2: The Influence of Mitochondria in Disease. 16: Diets to Support Mitochondrial Function. 17: Laboratory Tests and Biomarkers Related to Mitochondrial Function. 18: Insulin Resistance and Type 2 Diabetes. 19: Hypertension. 20: Heart Disease. 21: Cholesterol Metabolism. 22: Autoimmune Disease. 23: Fatigue. 24: Neurodegeneration. 25: Cancer. 26: Osteoarthritis. 27: Osteoporosis. 28: Chronic Pain. 29: Depression. 30: Autism Spectrum Disorders.

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Exploring the roles mitochondria play in human health, and how to optimize mitochondrial function through personalized nutrition

About the Author

Ray Griffiths is a nutritional therapist and lecturer with an MSc in Personalized Nutrition. Ray lectures on a diverse range of subjects such as Parkinson's disease, cancer, ageing and mitochondria.


The scope and detail of conditions covered within this book, combined with functional testing and appropriate interventions, offers a really useful handbook and tool to complement the practitioner in clinic. -- Nina Bailey BSc (Hons), MSc, PhD (Cantab), RNutr Head of Nutrition at Igennus Healthcare Nutrition
A thoughtful and thorough explanation of mitochondrial function and the role it plays in generating disease. This book is a combination of the latest scientific research with the practicalities of clinical application, making this book useful guide for practitioners and will certainly assist them in day to day practice. -- Leyla El Moudden, DipHerb DipNat mANP, General Secretary Association of Naturopathic Practitioners

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