Table of Contents

Preface vii
1 Crises in Biomedical Research 1
2 Philosophy of Models in Biology 17
3 A History of Animal Models 43
4 A History of In Vitro Models 77
5 Models and Therapies: Infectious Diseases, Cardiovascular Disease, and Cancer 107
6 Neurological Disorders: Trials and Tribulations 139
7 Diagnosis and Recommendations 175
Appendix 207
References 213
Index 283

About the Author

Georg Striedter is Professor in the Department of Neurobiology and Behavior at the University of California, Irvine. He is the author of two books on nervous system evolution, as well as an introductory college-level textbook, Neurobiology- A Functional Approach.