Table of Contents

I: The Poliovirus.- 1. History.- 2. Classification.- 3. Composition and Structure of the Virion.- 4. Structure and Function of the Genome.- II: The Replication of Poliovirus.- 5. Introduction.- 6. Morphological Alterations of the Host Cell as an Essential Basis for Poliovirus Replication.- 7. Early Interactions of Virus and Host Cell.- 8. Translation of the Viral Genome.- 9. Replication of the Viral RNA.- 10. Assembly of the Virion.- 11. Conclusions.- Appendix I: Laboratories Engaged in Poliovirus Research.- Appendix II: Poliovirus Models.- A. A Paper Model of a Prototype Picornavirus.- B. The Apple Model of Poliovirus.- Appendix III: The Geometry of Isometric Polyhedra.- A. The Platonic Polyhedra.- a) Models.- b) Characteristics.- c) Duality.- d) The Golden Proportion.- e) Geometric Restriction of the Maximal Number of Subunits.- B. Other Icosahedron-Related Polyhedra.- a) Characteristics.- b) The Triangulation-Number-Classification of Icosahedral Lattices.- Appendix IV: Complete Nucleotide and Amino Acid Sequences of Poliovirus Type 1, 2 and 3.- References.