Table of Contents

Charles A. Stiller and Gemma Gatta: 1 The epidemiology of cancer in children and adolescents
Kieran McHugh and Thierry A.G.M. Huisman: 2 Imaging in paediatric oncology
Michel Zwaan, Gareth J. Veal, and Lucas Moreno: 3 Chemotherapy and other anti-cancer drugs: current knowledge and new perspectives
Mark Gaze and Tom Boterberg : 4 Radiotherapy in paediatric oncology
Maria Grazia Valsecchi, Stefania Galimberti, and Pamela Kearns: 5 Clinical trials in childhood cancer
Leontien C. M. Kremer, Erik A.H. Loeffen, and Bob S. Phillips: 6 Evidence-based paediatric oncology
Adriana Balduzzi, Giovanna Lucchini, Jean-Hugues Dalle, and Rupert Handgretinger: 7 Allogeneic stem cell transplantation in children and adolescents with malignancies
Koichi Hirabayashi, Gianpietro Dotti, and Barbara Savoldo: 8 Cancer Immunotherapy in Children
Marianne van de Wetering and Bob S. Phillips: 9 Supportive care during treatment
Martha Grootenhuis, Momcilo Jankovic, Esther van den Bergh, and Femke Aarsen: 10 Psychosocial care
Michelle Koh, Finella Craig, and Joanne Wolfe: 11 Palliative Care for Children with Advanced Cancer
Elizabeth Molyneux, Trijn Israels, and Scott C. Howard: 12 Cancer treatment in low- and middle-income countries
Lucy J.W. Jones, Emmanouil Saloustros, Andrea Ferrari, and Dan Stark: 13 Cancer in Adolescents and Young Adults
Lars Hjorth, Riccardo Haupt, Gisela Michel, Maria Luisa Garrè, Leontien Kremerand, and Rod Skinner: 14 Late effects of therapy and survivorship issues
Denis Schewe, Mignon Loh, Rob Pieters, and Martin Schrappe: 15 Acute Lymphoblastic Leukemia
Gertjan Kaspers and Dirk Reinhardt: 16 Acute myeloid leukaemia
Henrik Hasle and Charlotte M. Niemeyer : 17 Myelodysplastic syndrome, myeloid leukaemia of Down syndrome, and juvenile myelomonocytic leukaemia
Véronique Minard-Colin and Catherine Patte: 18 Non-Hodgkin lymphomas in children and adolescents
Judith Landman-Parker and Françoise Montravers: 19 Hodgkin lymphoma: modern management of children and young adults
Maurizio Aricò, Cor van den Bos, and Sheila Weitzman: 20 Childhood histiocytoses
Michel Zerah, David Walker, and Shaarna Whitton : 21 Symptoms and emergencies in children with brain and spinal tumors
Dannis van Vuurden, Darren Hargrave, Dominik Sturm, and David T.W. Jones : 22 Glial CNS tumours of childhood
Maura Massimino, Eric Bouffet, and Vijay Ramaswamy : 23 Embryonal tumours
Cecile Faure Conter, Didier Frappaz, Kristian W. Pajtler, and Stefan M. Pfister : 24 Other CNS tumours of childhood
Hans Merks and Gianni Bisogno : 25 Soft tissue sarcomas
Stefan Bielack, Michael Paulussen, and Lee Helman : 26 Bone tumors
Norbert Graf and Christophe Bergeron : 27 Wilms' and other renal tumours
Angelika Eggert, Garrett Brodeur, and Gudrun Schleiermacher: 28 Neuroblastoma
Gabriele Calaminus and James C. Nicholson: 29 Germ Cell Tumours
Giorgio Perilongo and Jozsef Zsiros: 30 Childhood liver tumours
Guillermo Chantada and Carlos Rodríguez-Galindo: 31 Retinoblastoma

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Winner of the Oncology BMA Book Award 2021

About the Author

Andrea Biondi M.D., took the degree in Medicine in 1979 at the University of Milano, Italy and in 1982 and 1994 the Specialization in Pediatrics and Haematology respectively. In 1982-84 he was Research Associate in Pathology at the Dana Farber Cancer Institute-Harvard Medical School, Boston, USA. In 1986-1987 he was Research Associate in Medicine at the Ontario Cancer Institute, Toronto, Canada. Since November 2009, he has been the Director of the
Department and the School of Paediatrics, University of Milano-Bicocca, San Gerardo Hospital, Monza (MI), Italy. He is head of the M.Tettamanti Research Centre and of S. Verri Cellular and Gene Therapy Laboratory, San
Gerardo Hospital, Monza (MI), Italy. Since 2007 he has been Coordinator of the Ph.D. Program in Translational and Molecular Medicine at University of Milano-Bicocca, Milan, Italy. From 2004-08 he was President of SIOP Europe. His clinical and research interests relate to childhood leukaemia and to cell and gene therapy. Tom Boterberg graduated as an MD in 1994 at Ghent University. After one year of residency in radiation oncology, he worked for 4 years at the Laboratory of
Experimental Cancer Research on the biology of the invasive and metastatic behaviour of breast cancer cells. He obtained his PhD in 2000. Afterwards he continued his training in radiation oncology and in 2001 he obtained
his Board Certificate in Radiation Oncology. Since 2001 he works as a staff member at the Department of Radiation Oncology at Ghent University Hospital. He is especially interested in paediatric radiotherapy. He is actively involved in the radiotherapy committees of SIOPEN (neuroblastoma) and EpSSG (rhabdomyosarcoma). He is board member of SIOPE and chairs the QUARTET project on quality assurance in paediatric radiotherapy. He is author or co-author of over 100 articles in peer-reviewed
journals. His other interests are haematology, neuro-oncology, intra-operative brachytherapy and radioprotection. Hubert Caron graduated in medicine in 1985 from the Medical School, University of Amsterdam,
trained in paediatrics and in paediatric oncology in Emma Children's Hospital, AMC Amsterdam and was appointed professor in paediatric oncology in 2001. He received his PhD (cum laude) in 1995 on the subject "Chromosome 1P in Neuroblastoma: suppressors and prognosis". His main research interests are tumour biology, rational targeted drug design, early new drug trials, systematic reviews of effectiveness of interventions in paediatric oncology and late effects of treatment. Since 2014 he also
holds a position as medical director at Roche, where he is responsible for the global clinical development of the oncology portfolio of Roche for children with cancer. François Doz is professor of
Paediatrics at the University Paris Descartes and paediatric oncologist at Institut Curie, Paris. He got his MD, paediatric specialty and master in pharmacology in Paris. He then spent two years as a research fellow in the Brain Tumour Research Center, University of California, San Francisco. His main research interests are Paediatric Neuro-oncology, Retinoblastoma, Early Drug Development and Ethics of Clinical Research. He is past- member (2011-2013, 2017) and past-chair (2014-2016) of the
SIOP scientific committee, past-chair of the scientific committee of the SFCE (French paediatric cancer society) (2007-2011), member of the SIOPE Board, past- chair of the SIOP-Europe Brain Tumour Group
(2006-2010) and of its Medulloblastoma/PNET working group (2013-2016), member of the clinical trial committee and of the executive committee of the ITCC consortium (Innovative Treatment for Children with Cancer) and current co-chair of the European Retinoblastoma Group.

Reviews

This seventh edition has been thoroughly revised and updated, including brand new chapters on cancer immunotherapy in children, and cancer in adolescents and young adults, plus expanded treatment of tumours of the brain and central nervous system. The book primarily provides clear and up-to-date clinical guidance for use in treatment settings whilst offering a useful background to the biology of individual tumour types and the history of the development of specific treatments.
*Anticancer Research*