Table of Contents

Section 1: Hallmarks of Cancer
1: Douglas Hanahan and Robert A. Weinberg: The hallmarks of cancer
2: Shujuan Liu and Ahmed Ashour Ahmed: Growth factors and uncontrolled proliferation
3: Stefan Knapp: Cell signalling pathways
4: Simon Carr and Nicholas La Thangue: Cell cycle control
5: Amanda S. Coutts, Sandra Maniam, and Nicholas La Thangue: Cancer cell death
6: Yull E. Arriaga and Arthur E. Frankel: Angiogenesis
7: Andrew P. Mazar, Andrey Ugolkov, Jack Henkin, Richard Ahn, and Thomas V. O'Halloran: Invasion and metastases
8: Sir Walter Bodmer and Jenny Wilding: Genetic instability
9: E. Dikomey, K. Borgmann, M. Kriegs, W. Mansour, C. Petersen, and T. Rieckmann: DNA repair after oncological therapy
10: Andreas Trumpp: Biology of cancer stem cells
11: Richard D Kennedy, Manuel Salto-Tellez, D. Paul Harkin, and Patrick G Johnston: Biomarker identification and clinical validation
12: Campbell SD Roxburgh and Donald C McMillan: Cancer, immunity, and inflammation
13: Cameron Snell, Kevin C Gatter, Adrian L Harris, Francesco Pezzella: Cancer and metabolism
Section 2: Etiology and Epidemiology of Cancer
14: Jonathan Samet: Smoking and cancer
15: Chris Boshoff: Viruses
16: Paula A. Oliveira: Chemical carcinogens
17: Klaus Trott: Radiation
18: Ellen Kampman and Franzel van Duijnhoven: Body fatness, physical activity, diet, and other lifestyle factors
Section 3: Principles of Oncology
19: PG Boelens, CBM van den Broek, and CJH van de Velde: Practice points for surgical oncology
20: Annekatrin Singer, Stephanie E. Combs, Jürgen Debus, and Michael Baumann: Practice points for radiation oncology
21: David Kerr, Daniel Haller, and Jaap Verweij: Principles of chemotherapy
22: David N Church, Rachel S Midgley, and David J Kerr: Delivery of multidisciplinary cancer care
23: Michael Ong and Udai Banerji: Principles of clinical pharmacology: Introduction to pharmacokinetics and pharmacodynamics
24: Dan Sargeant and Qian Shi: Design and analysis of clinical trials
25: Eric A. Singer: Medical ethics in oncology
26: Jeffrey Peppercorn: Health economic assessment of cancer therapy
Section 4: Population Health
27: Masoud Samiei: Cancer control: The role of national plans
28: Sarah Goltz and Julian Lob-Levyt: Cancer prevention: Vaccination
29: Hans-Joerg Senn, Nadir Arber, and Dirk Schrijvers: Cancer prevention: Chemoprevention
30: Andrew Evans, Simon Herrington, and Robert Steele: Population cancer screening
31: Henry T. Lynch, Carrie L. Snyder, and Jane F. Lynch (deceased): Familial cancer syndromes and genetic counselling
Section 5: Support for the cancer patient
32: David Hui and Eduardo Bruera: Supportive palliative care
33: Neil Aaronson and Peter Fayers: Quality of life
34: Rachel L. Yung and Ann H. Partridge: Cancer survivorship and rehabilitation
Section 6: Disease
35: Christine Chung, Andreas Dietz, Vincent Gregoire, Marco Guzzo, Marc Hamoir, René Leemans, Jean-Louis Lefebvre, Lisa Licitra, Adel El-Naggar, Brian O?Sullivan, Bing Tan, Vincent Vandecaveye, Vincent Vander Poorten, Jan Vermorken, and Michelle Williams: Cancer of the head and neck
36: Eric Van Cutsem, Christophe M. Deroose, Piet Dirix, Karin Haustermans, Tony Lerut, Philippe Nafteux, Hans Prenen, and Xavier Sagaert: Oesophageal cancer
37: Hideaki Bando, Takahiro Kinoshita, Yasutoshi Kuboki, Atsushi Ohtsu, and Kohei Shitara: Gastric cancer
38: Regina Beets-Tan, Bengt Glimelius, and Lars Påhlman: Rectal cancer
39: John Zalcberg, Stephen Fox, Alexander Heriot, Jon Knowles, Sam Ngan, Michael Michael, Kathryn Field, and Iris Nagtegaal: Colon cancer
40: J. Weitz, M.W. Büchler, Paul D Sykes, John P Neoptolemos, Eithne Costello, Christopher M Halloran, Frank Bergmann, Peter Schirmacher, Ulrich Bork, Stefan Fritz, Jens Werner, Thomas Brunner, Elizabeth Smyth, David Cunningham, Brian R. Untch, and Peter J. Allen: Pancreatic cancer
41: Graeme J Poston, Nicholas Stern, Jonathan Evans, Priya Healey, Daniel Palmer, and Mohandas K. Mallath: Hepatobiliary cancer
42: H. Richard Alexander, Jr., Dario Baratti, Terence C. Chua, Marcello Deraco, Raffit Hassan, Marzia Pennati, Federica Perrone, Paul H. Sugarbaker, Anish Thomas, Keli Turner, Tristan D. Yan and Nadia Zaffaroni: Peritoneal mesothelioma
43: Martine Piccart, Toral Gathani, Dimitrios Zardavas, Hatem A. Azim Jr., Christos Sotiriou, Giuseppe Viale, Emiel J T Rutgers, Mechthild Krause, Monica Arnedos, Suzette Delaloge, Fabrice Andre, and Felipe Ades: Cancer of the breast
44: Richard Pötter, Shujuan Liu, Bolin Liu, Sebastien Gouy, Sigurd Lax, Eric Leblanc, Philippe Morice, Fabrice Narducci, Alexander Reinthaller, Maximilian P Schmid, Catherine Uzan, and Pauline Wimberger: Gynaecological cancers
45: John Fitzpatrick, Asif Muneer , Jean de la Rosette, and Thomas Powles: Genitourinary cancer
46: Rafal Dziadziuszko, Michael Baumann, Tetsuya Mitsudomi, Keith M. Kerr, Solange Peters, and Stefan Zimmermann: Lung cancer
47: Rebecca Bütof, Axel Denz, Gustavo Baretton, Jan Stöhlmacher-Williams, and Michael Baumann: Neoplasms of the thymus
48: Andrea S. Wolf, Assunta De Rienzo, Raphael Bueno, Lucian R. Chirieac, Joseph Corson, Elizabeth H. Baldini, David Jackman, Ritu Gill, Walter Weder, Isabelle Opitz, Ann S. Adams, and David J. Sugarbaker: Pleural mesothelioma
49: John F Thompson, Richard A Scolyer, and Richard F Kefford: Skin cancer: melanoma
50: Diona L. Damian, Richard A. Scolyer, Graham Stevens, Alexander Menzies, and John F. Thompson: Skin cancer: non-melonoma
51: Adele K. Fielding, Charles G. Mullighan, Dieter Hoelzer, Eytan M. Stein, Ghada Zakout, Martin S. Tallman, Ross Levine, Yishai Ofran, Jacob M. Rowe, and Ross L. Levine: Acute leukemia
52: Hemant Malhotra, Lalit Kumar, Pankaj Malhotra, Devendra Hiwase, and Ravi Bhatia: Chronic leukemias
53: Charlotte Pawlyn, Faith Davies, and Gareth Morgan: Myeloma
54: Frank Kroschinsky, Friedrich Stölzel, Stefano A. Pileri, Bjoern Chapuy, Rainer Ordemann, Christian Gisselbrecht, Tim Illidge, David C. Hodgson, Mary K. Gospodarowicz, Christina Schütze, and Gerald Wulf: Lymphomas
55: Alessandro Gronchi, Angelo P. Dei Tos, and Paolo G. Casali: Sarcomas of the soft tissue
56: Puneet Plaha, Allyson Parry, Pieter Pretorius, Michael Brada, Olaf Ansorge, and Claire Blessing: Cancer of the central nervous system
57: Daniel G. Ezra, Geoffrey E. Rose, Jacob Pe'er, Sarah Coupland, S. Seregard, G.P.M. Luyten, and Annette C. Moll: Cancer of the eye and orbit
58: David Kerr, Andrew Weaver, Anthony P. Weetman, Oliver Gimm, Ashley Grossman, Petra Sulentic, Bertram Wiedenmann, Ulrich-Frank Pape, John Wass, Angela Rogers, and W de Herder: Endocrine cancers
59: Nicholas Pavlidis and George Pentheroudakis: Cancer of unknown primary site
Index

About the Author

David J. Kerr, Professor of Cancer Medicine, Nuffield Division of Clinical Laboratory Sciences, Nuffield Department of Medicine, University of Oxford, Oxford, UK, Honorary Professor of Oncology, Xiamen and 2nd Military Universities, China, Honorary Professor, Seoul National University, Korea, Daniel G. Haller, Professor Emeritus, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA, Cornelis J. H. van de Velde, Professor of Surgery and Head, Department of Surgical Oncology, Leiden University Medical Center, The Netherlands, Michael Baumann, Cancer Research Center (DKFZ), Heidelberg, Germany and Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universitat Dresden, Germany

Reviews

I would recommend anyone considering buying an oncology textbook, and particularly those who work in oncology support services, to consider this textbook as it is well set out, easy to read, easy to comprehend, and covers all of the important aspects of modern day oncology.
*Dr Andrew Davies, Consultant in Palliative Medicine, Royal Surrey County Hospital; Review for Supportive Care in Cancer*

An outstanding gift to the international scientific community... The new textbook is an excellent demonstration of this multifaceted and astonishingly variable problem, as well as of the latest achievements in its understanding and practical management.
*Alexander A. Shtil, Recent Patents on Anticancer Drug Discovery*

This volume provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.
*Anticancer Research Vol. 36 (2016)*

The Oxford Textbook of Oncology is what it is meant to be: a textbook with comprehensive information of the actual status of oncology... an indispensable and attractive source of information.
*Professor Jaak Ph. Janssens, European Journal of Cancer Prevention*

Reviews from the previous edition

The Oxford Textbook of Oncology is a classic and fresh approach to the field. It is a must for all libraries and all those who like to have a single up-to-date reference book that contains sufficient detail for the clinician in all subspecialties: surgery and chapters are sufficiently details to provide a reference for trainees in the field.
*Oncology, Volume 63, 2002*

The Oxford Textbook of Oncology covers virtually the entire spectrum of malignant diseases in adults and children. It meets very high editorial and production standards: the organization, illustrations, and eye-pleasing typography are outstanding... I have high praise for this textbook.
*NEJM, Volume 347, Number 2, 2002*

Under new editorship, the second edition is far more than an updated version of the first...the prose in the Oxford Textbook is exemplary...this textbook is unique among its peers in giving the sense that the authors are addressing the reader personally...an exception level of quality…Respect for the evidence-based medicine is apparent throughout the text...illustrative and anatomical drawing...of remarkable high quality...excellent discussion of doctor-patient communication in relation OT genetic counselling, psychological issues, and terminal cancers.
*JAMA, Volume 287, Issue 24, 2002*

A landmark reference…It sets new standards for publishing in oncology offering a ground-breaking innovative approach to the filed combined with the quality, accuracy , and intellectual rigour you have come to expect from the world's most prestigious reference publisher.
*Biomedicine and Pharmacotherapy, 2002*

This comprehensive textbook of oncology is the first new major textbook on cancer to appear in a decade and is designed for a broad audience of clinicians, oncologists in training, and academics. The coverage is comprehensive...The overall appearance of the book is outstanding. It is a welcome combination of epidemiology, aspects of basic science, pharmacology and radiation therapy that trainees will fine a nice change...should enjoy a wide readership...because of its appealing design and comprehensive approach to oncology. It is the most user-friendly comprehensive text currently available. The pathology, basic science, epidemiology, and radiation therapy sections are all presented with extreme clarity.
*Doody's Journal , 2002*

I recommend this book highly to all oncology and oncologists in training as a thorough, informative, and readable reference. Every large intuitional library and every oncology library should have it.
*NEJM, 2002*

Each chapter is nicely illustrated with schemes, cartoons and images. The text, although written by top oncologists, is readily understandable for a non-expert. Thus, the textbook will no doubt be appreciated by a broader audience.
*Recent Patents on Anti-Cancer Drug Discovery Vol. 11 Issue No. 4, Alexander Shtil*