Table of Contents

Section 1: Ductal Adenocarcinoma of the Pancreas

1. Histologic Classification and Tumor Staging of Pancreatic Cancer
Akio Yanagisawa and Eiichi Konishi

2. What We Know about Carcinogenesis of Ductal Adenocarcinoma of the Pancreas
C. J. Bruns, H. Niess, B. Schwarz, A. Kleespies, M. K. Angele and K.-W. Jauch

3. Familiar Cancer of the Pancreas
Detlef K. Bartsch, Volker Fendrich and Peter Langer

4. Clinical, Laboratory and Radiologic Presentation of Pancreatic Cancer
Susumu Hijioka and Kenji Yamao

5. Standards of Oncologic Pancreatic Surgery
Zhi Ven Fong and Keith D. Lillemoe

6. Extended Resection for Pancreatic Cancer: Risk and Benefits
Akimasa Nakao

7. Risk/Benefit of Total Pancreatectomy for Pancreatic Cancer: Are There Indications?
Ake Andrén-Sandberg and Ralf Segersvard

8. Is There a Benefit for Additional Arterial Resection of Ductal Cancer of the Pancreas?
Satoshi Hirano and Takahiro Tsuchikawa

9. Who Benefits from Ultra-Radical Pancreatic Cancer Extirpation?
Akimasa Nakao

10. Risk and Results of Pancreatic Cancer Resection
Norbert Hüser, Volker Assfalg and Helmut Friess

11. Pancreatic Cancer: The Role of Bypass Procedures
J.A.M.G. Tol, O.R.C. Busch, T.M. van Gulik and D.J. Gouma

12. Evidence of Adjuvant Chemotherapy of Ductal Pancreatic Cancer
Asma Sultana, Christopher Halloran, Daniel Palmer, Paula Ghaneh Trevor Cox and John P Neoptolemos

13. Neoadjuvant Chemo- and Radio-Chemotherapy: Is There a Survival Advantage for Pancreatic Cancer Patients
Susan Tsai, Ben George, Kathleen K. Christians and Douglas B. Evans

14. Standards of Palliative Chemotherapy and Chemoradiotherapy of Local Advanced Pancreatic Cancer, Side Effects and Survival Benefits
Hana Algül and Roland M. Schmid

15. Management of Local and Distant Recurrence after Pancreatic Cancer Resection
Takuji Okusaka, Kenji Hashimoto, Tomoko Katsui Taniyama, Hideki Ueno, Chigusa Morizane, Shunsuke Kondo, Shuichi Mitsunaga, Satoshi Shimizu, Izumi Ohno, Hideaki Takahashi and Masafumi Ikeda

16. Survival 3-, 5- and 10-years after Adjuvant Regional and Neoadjuvant Chemotherapy in Resectable Pancreatic Cancer Patients: an Institutional Experience
Osamu Ishikawa, Hiroaki Ohhigashi and Hidenori Takahashi

17. Non-ductal Primary Malignancies of the Pancreas: Acinus Cell Carcinoma
Marius Distler and Robert Grutzmann

18.Non-ductal Primary Malignancies of the Pancreas: Metastatic Malignancies
Victor Zaydfudim, Michael B. Farnell and Michael G. Sarr

Section 2: Periampullary Cancers

19. Histopathology of Tumor of the Ampulla of Vater
Li-rong Chen

20. Clinics of Periampulary Cancer
Cai Xiujun

21. Adenoma of the Papilla of Vater and Endoscopic Management
Takao Itoi and Shujiro Tsuji

22. Controversies about Local or Regional Treatment of Adenoma of the Papilla of Vater: Japanese Experience
Takehiro Ota, Masakazu Yamamoto and Ken Takasaki

23. Cancer of the Papilla: Surgical Management
Hans G. Beger Q L Qiao and B Poch

24. Evidence of Surgical Management of Distal Common Bile Duct Cancer
Yingbin Liu and Wenguang Wu

25. Evidence of Surgical Management of Duodenum Cancer
Rory L. Smoot and Florencia G. Que

26. Survival and Chance of Cure after Surgery, Adjuvant and Palliative Chemotherapy of Periampullary Tumors
Hao ran Qian and Shu You Peng

Section 3: Cystic Neoplastic Lesion of the Pancreas

27. Histologic Classification and Staging of Cystic Neoplastic Lesions of the Pancreas
Rondell Graham and Tom Smyrk

28. Clinical Presentation of Cystic Neoplasms of the Pancreas
Masao Tanaka

29. EUS and Cystic Fluid Analysis of the Pancreas: Evidence of Diagnostic Measures
Won Jae Yoon and William R. Brugge

30. Natural History of IPMN: Adenoma/Carcinoma Sequence in IPMN
Masanori Sugiyama and Yutaka Suzuki

31. What are the Pathologic Criteria that Justified Observational Management in Patients with Cystic Naoplastic Lesions of the Pancreas?
Klaus Sahora, and Carlos Fernández-del Castillo

32. Indication for Operative Intervention of Cystic Neoplasms of the Pancreas
George H. Sakorafas and Vassileios Smyrniotis

33. Surgical Management of IPMN Lesions of the Pancreas
Marcus C.B. Tan and Peter J. Allen

34. Surgical Management of MCN Lesions of the Pancreas
Klaus Sahora and Carlos Fernández-del Castillo

35. Surgical Management of SCA of the Pancreas
Giuseppe Malleo, Claudio Bassi and Roberto Salvia

36. Surgical Management of SPsN of the Pancreas
Song Cheol Kim

37. Limited Oncologic Resection or Major Surgery of Cystic Neoplasms of the Pancreas?
Hans G Beger, Yang Yinmo, and Akimasa Nakao

38. Enucleation of Cystic Neaplasia of the Pancreas?
Janak A. Parikh and C. Max Schmidt

39. Long-Term Outcome after Observation and Surgical Treatment of the Cystic Neoplasms of the Pancreas
Giuseppe Malleo, Roberto Salvia and Claudio Bassi

Section IV: Endocrine Neoplasms of the Pancreas

40. Classification of Endocrine Tumors of the Pancreas
J. J. Mukherjee and K. O. Lee

41. Clinical Manifestation of Endocrine Tumors of the Pancreas
K. O. Lee

42. Evidence of Hormonal, Laboratory, Bio-Chemistric and Instrumental Diagnostics of Endocrine Tumors of the Pancreas
C.E.D.Ng, J. J. Mukherjee and K.O. Lee

43. Evidence of Medical and Radionucleotide Treatment of Endocrine Tumors of the Pancreas
David C.E. Ng., J. J. Mukherjee and K.O. Lee

44. Insulinoma: Evidence of Surgical Treatment
Y. P. Mou

45. Gastrinoma: Evidence of Surgical Treatment
R. Y. Qin

46. Rare Endocrine Tumors of the Pancreas: Evidence of Management
Jiang Tao Li, Shu You Peng and De Fei Hong

47. Long-term Outcome after Clinical Management of Endocrine Tumors of the Pancreas
Bin Xu and Jian Wei Wang

Section V: Chronic Pancreatitis with Inflammatory Tumor of the Pancreas

48. Chronic Pancreatitis with Inflammatory Mass in the Pancreatic Head
Ulrich F. Wellner and Tobias Keck

49. Chronic Tropical Pancreatitis: Clinical syndromes, natural course management principles
Savio G. Barreto and Shailesh V. Shrikhande

50. Laboratory, Endoscopic and Radiologic Diagnostic of Chronic Pancreatitis with Inflammatory Mass in the Head
J. Enrique Domínguez-Munoz, Julio Iglesias-Garcia and José Larino-Noia

51. Autoimmune Pancreatitis : How to Recognize this Entity and Avoid Surgical Treatment
Raghuwansh P. Sah and Suresh T. Chari

52. What is the Place of Interventional-Endoscopic Treatment in Chronic Pancreatitis/Inflammatory Tumor of the Pancreatic Head?
Yoshiki Hirooka and Hidemi Goto

53. When to Change from Conservative to Surgical Management in Alcoholic Chronic and Tropical Chronic Pancreatitis
Shailesh V. Shrikhande and Savio G. Barreto

54. Duodenum Preserving Pancreatic Head Resection of Chronic Pancreatits with Inflammatory Mass
Hans G. Beger and Qiao Qilu

55. Major Resection for Chronic Pancreatitis
John C. McAuliffe and John D. Christein

56. Short-term and Long-term Outcome after Interventional and Surgical Treatment of Chronic Pancreatitis with Inflammatory Mass
Volker Assfalg, Norbert Hüser and Helmut Friess

About the Author

Hans G. Beger MD, FACS, Emeritus Professor of Surgery, Universitätsklinikum Ulm, Universität Ulm, Ulm, Germany.

Akimasa Nakao MD, PhD, FACS, Professor Emeritus, Nagoya University; President, Nagoya Central Hospital, Nagoya, Japan.

John P. Neoptolemos MA, MB, BChir, MD, FRCS, FMedSci, The Owen and Ellen Evans Chair of Surgery; NIHR Senior Investigator; NIHR Liverpool Pancreas Biomedical Research Unit, The Liverpool Clinical Trials Unit and Cancer Research UK; Cancer Trials Unit Director, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

Shu You Peng MD, FACS, FRCSG, ESA, Professor, Department of Surgery, Second Affi liated Hospital, Zhejiang University, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.

Michael G. Sarr MD, J.C. Masson Professor of Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA.