Preface 7
Abbreviations 8
General pathology
Introduction
1 The normal human cell 12
2 Fluid dynamics 14
Tissue damage
3 Tissue types and the effects of tissue damage 16
4 Cell death 18
5 Harmful agents in the environment 20
6 The effects of tobacco alcohol and other drugs 22
7 Nutritional disorders 24
Inflammation and immunity
8 The body’s natural defences 26
9 B cells and immunoglobulins 28
10 T cells 30
11 The major histocompatibility complex 32
12 The reticuloendothelial system 34
13 Acute inflammation 36
14 Chronic inflammation 38
15 Wound healing and repair 40
16 Infection and immunodeficiency 42
17 Shock 44
18 Tolerance and autoimmune disease 46
19 Hypersensitivity reactions 48
20 Overview of inflammation and immunity 50
Genetics
21 Cell division 52
22 Genetic disease 54
Neoplasia
23 Disordered cell growth 56
24 Basic concepts in neoplasia 58
25 Tumorigenesis and oncogenesis 60
26 Oncogenes and tumour suppressor genes 62
27 Common carcinoma histological subtypes 64
28 Tumour prognosis and treatment 66
Systems pathology
Multisystems disease
29 Sarcoidosis and syphilis 70
30 Wilson’s disease and haemochromatosis 72
31 Systemic vasculitis 74
Cardiovascular disease
32 Normal blood vessels and types of aneurysm 76
33 Congenital heart disease 78
34 Systemic hypertension 80
35 Atherosclerosis 82
36 Ischaemic heart disease 85
37 Thrombosis 88
38 Embolism and disseminated intravascular coagulation 91
39 Cardiac valvular disease 94
40 Myocardial and pericardial disease 96
Respiratory disease
41 Pulmonary vascular disorders 98
42 Pneumonia 100
43 Bronchiectasis 102
44 Tuberculosis 104
45 Chronic obstructive pulmonary disease 106
46 Fibrosing alveolitis 108
47 Primary lung carcinoma 110
48 Other tumours of the lung and pleura 112
Gastrointestinal tract disease
49 Malabsorption 114
50 Peptic ulceration and Helicobacter pylori 116
51 Oesophageal disease 118
52 Tumours of the stomach and small intestine 120
53 Mechanical disease of the gastrointestinal tract 122
54 Ulcerative colitis and Crohn’s disease 124
55 Adenomatous polyps colorectal cancer and anal carcinoma 126
Hepatic and pancreaticobiliary disease
56 Normal liver and the effects of liver damage 128
57 Jaundice gallstones and carcinoma of the gallbladder 130
58 Alcoholic and non-alcoholic liver disease 132
59 Autoimmune hepatitis and cholangiopathies 134
60 Viral hepatitis 136
61 Cirrhosis 139
62 Acute and chronic pancreatitis 142
63 Tumours of the liver biliary tree and pancreas 144
Genitourinary tract disease
64 Congenital and inherited abnormalities of the kidney and urinary tract 146
65 The nephron and renal aspects of hypertension 148
66 Glomerulonephritis 150
67 Important types of glomerulonephritis 152
68 Tubulointerstitial diseases 154
69 Renal neoplasms 156
70 Bladder tumours 158
71 Testicular cancer 160
72 Prostatic disease 162
Gynaecological and obstetric disease
73 Ovarian tumours 164
74 Benign uterine conditions 166
75 Uterine cancer 168
76 Cervical cancer 170
77 Obstetric pathology 172
78 Paediatric tumours 174
Nervous system disease
79 Cerebrovascular accidents 176
80 Cerebrovascular accident syndromes 178
81 Raised intracranial pressure 179
82 Traumatic injury and intracranial haemorrhage 180
83 Central nervous system tumours 182
84 Infections of the nervous system 184
85 Movement disorders 186
86 Acquired disorders of myelination 188
87 Dementia 190
Endocrine disease
88 Pituitary pathology 192
89 Non-neoplastic pathology of the thyroid 194
90 Thyroid neoplasms 196
91 Parathyroid gland pathology 198
92 Adrenal pathology 200
93 Diabetes mellitus 202
Head and neck pathology
94 Head and neck pathology 204
Lymphoreticular disease
95 Lymphoma 206
96 Myeloma 208
97 Assorted haematological conditions 210
Musculoskeletal disease
98 Muscle disorders 212
99 Arthritis 214
100 Miscellaneous non-neoplastic osteoarticular pathology 216
101 Bone tumours 218
Skin disease
102 Inflammatory dermatoses 220
103 Benign skin tumours 222
104 Malignant skin tumours 224
Breast disease
105 Benign breast disease 226
106 Breast carcinoma 228
Self-assessment
Case studies and questions 230
Answers 235
Glossary 240
Reference ranges 242
Index 243
Caroline Finlayson St George's Hospital Medical School,
London.
Barry Newell St George's Hospital Medical School, London.
"Pathology at a Glance sets a standard in how illustrators and authors combine their creative skills to provide an enjoyable learning experience. The text is succinct yet includes all recent developments." (Journal of Tropical Pediatrics, December 2009)
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