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Table of Contents

1 Large Models in the Study of Protein Metabolism.- 2 Optimal Experiment Design in Plasma Protein Metabolic Studies: Sequential Optimal Sampling Schedules for Quantifying Kinetics.- 3 Formulation, Identification and Validation of Mathematical Models for Plasma Protein Metabolic Studies.- 4 Kinetic Modelling for Distribution and Removal of Plasma Proteins with Altered Biological Behaviour in vivo.- 5 Regulation of the Interstitial Distribution of Plasma Proteins.- 6 In vivo and in vitro Regulation of Albumin Synthesis.- 7 In vitro and in vivo Regulation of Immunoglobulin Synthesis.- 8 IgA Immunoglobulin Synthesis, Catabolism and Transport.- 9 Regulation of Retained and Secreted Liver Proteins.- 10 Metabolism of Radiolabelled Complement Proteins in Health and Disease.- 11 Metabolic Studies of Acute-phase Proteins.- 12 Significance of in vivo and in vitro Metabolic Studies of Tumour-produced Proteins.- 13 Fibrinogen and Fibrinogen-related Peptides in Cancer.- 14 Studies of Antithrombin Turnover.- 15 Nutritional Aspects of Plasma Protein Metabolic Studies: Protein-Energy Malnutrition.- 16 Nutritional Aspects of Plasma Protein Metabolic Studies: Long-term Treatment of Chronic Uraemia by a Very-low-protein Diet Supplemented with Essential Amino Acids and Keto Analogues.- 17 Kinetics of Apolipoproteins A-I and A-II.- 18 The Plasma Apolipoproteins: Physiological Properties and Possible Role in Lipid Disorders and Atherogenesis.- 19 Role of Cell-Surface Receptors in the Behaviour in vivo of Transferrin.