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Pediatric Solid Organ Transplantation
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Table of Contents

Section 1 Immunology and Genetics.

1 The Immune Response to Organ Allografts.

Manikkam Suthanthiran.

2 Allorecognition Pathways.

Nader Najafian and Mohamed H. Sayegh.

3 Costimulation.

Elizabeth Ingulli and David M. Briscoe.

4 The HLA System and Histocompatibility Testing for Organ Transplantation.

René J. Duquesnoy.

5 Gene Polymorphisms and Pharmacogenomics.

Robyn Temple-Smolkin, Gilbert J. Burckart and Adriana Zeevi.

6 Genomics and Proteomics as Research Tools.

Elaine S. Mansfield and Minnie M. Sarwal.

7 Tolerance: A Review of its Mechanisms in the Transplant Setting.

Alan D. Salama.

Section 2 Immunosuppression and its Complications.

8 Mechanisms of Action of Immunosuppressive Agents.

Alan M. Krensky.

9 Induction and Maintenance Immunosuppression.

William E. Harmon.

10 Novel Immunosuppressants.

Flavio Vincenti and Ryutaro Hirose.

11 Therapies for the Allosensitized Patient.

Alice Peng and Stanley C. Jordan.

12 Infections Post-Transplantation.

Michael Green and Marian G. Michaels.

13 Post-Transplant Lymphoproliferative Disorders and Malignancy.

Steven A. Webber and Michael Green.

14 Organ Toxicities.

Vikas R. Dharnidharka, Carlos E. Araya and Mark R. Benfield.

Section 3 Kidney Transplantation.

15 Historical Notes.

Vassilios E. Papalois and John S. Najarian.

16 Recipient Characteristics.

Sharon M. Bartosh.

17 Evaluation of the Candidate.

Uptal D. Patel and Susan E. Thomas.

18 Donor Evaluation, Surgical Technique and Perioperative Management.

Zoran Vukcevic, Demetrius Ellis, Mark Bellinger and Ron Shapiro.

19 Pathology of the Kidney Allograft.

Arthur H. Cohen.

20 Post-Transplant Management.

Jodi M. Smith and Ruth A. McDonald.

21 Outcomes and Risk Factors.

Alicia M. Neu and Barbara A. Fivush.

Section 4 Liver Transplantation.

22 Historical Notes.

Silvio Nadalin, Massimo Malagó and Christoph E. Broelsch.

23 Recipient Characteristics.

Udeme D. Ekong, Estella M. Alonso and Peter F. Whitington.

24 Evaluation of the Candidate.

Binita M. Kamath and Elizabeth B. Rand.

25 Donor Evaluation, Surgical Technique and Perioperative Management.

Jean C. Emond, Steven J. Lobritto and Dominique Jan.

26 Pathology of the Liver Allograft.

Maria Parizhskaya and Ronald Jaffe.

27 Post-Transplant Management.

Kyle Soltys, Robert Squires, Rakesh Sindhi and George V. Mazariegos.

28 Outcomes and Risk Factors.

Marc L. Melcher and John P. Roberts.

Section 5 Heart Transplantation.

29 Historical Notes.

Steven A. Webber and William H. Neches.

30 Recipient Characteristics.

Charles E. Canter and David C. Naftel.

31 Evaluation of the Candidate.

Gerard J. Boyle.

32 Donor Evaluation, Surgical Technique and Perioperative Management.

Frank A. Pigula and Steven A. Webber.

33 Pathology of the Cardiac Allograft.

Maria Parizhskaya.

34 Post-Transplant Management.

Shelley D. Miyamoto and Biagio A. Pietra.

35 Outcomes and Risk Factors.

W. Robert Morrow and Richard E. Chinnock.

Section 6 Lung and Heart-Lung Transplantation.

36 Historical Notes.

Eric N. Mendeloff.

37 Recipient Characteristics.

Eithne F. MacLaughlin.

38 Evaluation of the Candidate.

Albert Faro, Gary Visner and George B. Mallory.

39 Donor Evaluation, Surgical Technique and Perioperative Management.

Charles B. Huddleston.

40 Pathology of the Lung Allograft.

Paul S. Dickman.

41 Post-Transplant Management.

Marlyn S. Woo.

42 Outcomes and Risk Factors.

Stuart C. Sweet.

Section 7 Intestinal Transplantation.

43 Historical Notes.

Jorge Reyes.

44 Recipient Characteristics.

Jean F. Botha and Debra L. Sudan.

45 Evaluation of the Candidate.

Stuart S. Kaufman.

46 Donor Evaluation, Surgical Technique and Perioperative Management.

Thomas M. Fishbein and Cal S. Matsumoto.

47 Pathology of the Intestinal Allograft.

Maria Parizhskaya and Ronald Jaffe.

48 Post-Transplant Management.

Erick Hernandez, Tomoaki Kato, Andreas G. Tzakis and John F. Thompson.

49 Outcomes and Risk Factors.

Douglas G. Farmer.

Section 8 Special Issues after Pediatric Transplantation.

50 Growth and Puberty.

Franz Schaefer.

51 Cognitive Development.

Erik Qvist, Hannu Jalanko and Christer Holmberg.

52 Psychosocial Adaptation and Adherence.

Eyal Shemesh.

53 Pregnancy.

Vincent T. Armenti, Michael J. Moritz and John M. Davison.

54 Gynecologic Issues.

Gina S. Sucato and Pamela J. Murray.

55 Transition to Adult Care.

Janet McDonagh and Deirdre A. Kelly.

Index

About the Author

Professor Richard Fine, Professor and Chairman, Department of Paediatrics, State University of New York, USA

Dr Steve Webber, Division of Cardiology, Children's Hospital of Pittsburgh, USA

Dr William Harman, Associate Professor of Paediatrics, Harvard Medical School, Boston, USA

Reviews

"This is a useful and readable reference for the pathologist, but mainly because of the basic scientific and clinical information provided rather than for its coverage of allograft pathology." (Pediatric and Developmental Pathology) "This remains the only text devoted to pediatric transplant issues and accomplishes the stated goals...It serves to fill a void in the field." (Doody's Review Service) "A comprehensive text written by experienced authors on all aspects of solid organ transplantation." (Paediatric Endocrinology Reviews)

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