Table of Contents

1. Pathophysiology of Pain and Pain Pathways
Paula Trigo Blanco, Maricarmen Roche Rodriguez, and Nalini Vadivelu

2. Preventative Analgesia for the Management of General Surgical Pain
Mohammed Asif Qureshi, J.H. Gan, Sree Kunnumpurath, Clara Pau, Alice Kai, Zachariah Mirsky, William Park, and Nalini Vadivelu

3. Perioperative Nonopioid Analgesics of Use in Pain Management for Spine Surgery
Kenneth Fomberstein, Michael Rubin, Dipan Patel, Ivona Truszkowska, and S. Gabriel Farkas

4. Perioperative Opioid Analgesics of Use in Pain Management for Spine Surgery
Kenneth Fomberstein, Marissa Rubin, Dipan Patel, John-Paul Sara, and Abhishek Gupta

5. Local Anesthetics
Donna Thomas

6. Susceptibility of Peripheral Nerves in Diabetes to Compression and Implications in Pain Treatment
Natalia Murinova and Daniel Krashin

7. Cervical Spine
Siddarth Thakur and Salahadin Abdi

8. Thoracic Spine Pain
Mark R. Jones, Matthew Novitch, Graham R. Hadley, Alan D. Kaye, and Sudhir A. Diwan

9. Lumbosacral Spine
Chang-Yeon Kim, Charles Chang, Raysa Cabrejo, and James Yue

10. Lumbar Neurogenic Claudication: Causes and Pain Management Options
Raj Gala and James Yue

11. Needle Placement
Kenneth D. Candido and Teresa M. Kusper

12. Sacroiliac Pain: Causes and Pain Management Options
Rene Przkora, Richard Cleveland Sims, and Andrea Trescot

13. Sympathetic Pain Syndromes
Kenneth D. Candido and Teresa M. Kusper

14. Comprehensive Review of Discography in Spinal Pain
Graham R. Hadley, Matthew Novitch, Mark R. Jones, Vwaire Orhurhu, Alan D. Kaye, and Sudhir A. Diwan

15. Open Endoscopic Rhizotomy
Raj Gala, Lauren Szolomayer, and James Yue

16. Endoscopically Assisted Lumbar Medial Branch Rhizotomy
Lauren Szolomayer, Raysa Cabrejo, James Yue, and Raj Gala

17. Advances in Dorsal Column Stimulation
Chirag D. Shah and Maunak V. Rana

18. Advances in Intrathecal Drug Delivery: Impact on Orthopedic Practice
Jay S. Grider, Michael E. Harned, and Vital Nagar

19. Neuromodulation and Spinal Cord Stimulators: A Long Overdue Paradigm Disruption with the Interventional Pain Management Ladder
Anh L. Ngo, Bruce A. Piszel, Mark R. Jones, Hector J. Cases, Alan D. Kaye, and Mark V. Boswell

About the Author

John S. Reach, Jr., MSc, MD, is Section Chief and Director of Yale's Orthopaedic Foot & Ankle Surgery Division. He is also Associate Professor of Orthopedic Surgery at Yale University School of Medicine in New Haven, CT. He has won the prestigious Vernon Nickel Award for outstanding research concerning the preservation or restoration of musculoskeletal function, the Keith & Marion Moore Blue Box Anatomy Award, and the Mayo Clinic Patrick J. Kelly
Award.

James J. Yue, MD, is co-chief of the orthopaedic spine surgery section at the Yale School of Medicine. He is director of the Yale Spine Fellowship as well as the lead surgeon for motion sparing as well as endoscopic spine surgery. He has been the Principal Investigator/Co-Investigator on a number of FDA and non FDA clinical trials for disc replacement and endoscopic spine surgery. He is the Chair of the Education Committee for the International Society for the Advancement of Spine Surgery and
IITTSS spine society.

Deepak Narayan, MD, is a Professor of Surgery at the Yale University School of Medicine in New Haven, CT. He is also the Chief of Plastic Surgery at the Veterans Affairs Medical Center in West Haven, CT. In addition to a busy clinical practice he is actively involved in research and has a special interest in postoperative pain.

Alan David Kaye, MD, PhD, DABA, DABIPP, DABPM, FASA is the Tenured Professor, Program Director, and Chairman of the Department of Anesthesiology at LSU Health Sciences Center in New Orleans since 2005. He received two BS degrees and a MD degree from the University of Arizona. Dr. Kaye also completed his PhD in pharmacology at Tulane School of Medicine. Dr. Kaye has been awarded top doctors honors in the fields of anesthesiology and pain management.

Nalini Vadivelu, MD, graduated from Medical school in Christian Medical college, Vellore, India, and completed her Anesthesiology Residency in the University of Southern California. She completed her Pain Management Fellowship in Memorial Sloan Kettering Cancer Center, New York. She has been working as faculty at Yale University since 2002.

Reviews

"Orthopaedic and spine operations often cause the most intense post-surgery acute pain conditions. Therefore this is a useful up-to date review of most aspects of perioperative pain management for orthopaedic and spine surgery, of special interest for surgeons, anaesthetists, and other health providers." -- Harald Breivik, Scandinavian Journal of Pain