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Post-Transplant Lymphoproliferative Disorders


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Table of Contents

Introduction and History.- Definitions and Pathology of PTLD.- EBV Biology in the Pathogenesis of PTLD.- Host genetic mutations and expression analyses in PTLD.- Immune responses to EBV in the immunocompromised host.- Technical aspects of Epstein-Barr viral load assays.- Epidemiology of PTLD after SOT.- Clinical Features and Diagnostic Considerations.- Prognostic Factors.- Management of PTLD.- Prevention of Epstein - Barr virus Infection and Post-Transplant Lymphoproliferative Disorders Following Transplantation.- Epidemiology and Prognosis of PTLD after HSCT.- Clinical Presentations and Features of PTLD after Hematopoietic Stem Cell Transplantation.- Management of PTLD after HSCT.- Preventative and preemptive strategies for EBV infection and PTLD after hematopoietic stem cell transplantation.- Organ Specific issues of PTLD – Kidney.- Liver.- Post-transplantation Lymphoproliferative Disorder in Intestinal Transplant Recipients.- PTLD After Heart Transplantation.- Lung Transplantation.- Research Priorities and Future Directions.

About the Author

Vikas R. DharnidharkaDivision of Pediatric Nephrology Hypertension and PheresisWashington University School of MedicineSt. Louis, MOUSA Michael GreenDepartments of Pediatrics and SurgeryUniversity of Pittsburgh School of MedicineUPMC Children's Hospital of PittsburghPittsburgh, PAUSA Steven A. WebberDepartment of PediatricsVanderbilt University School of MedicineNashville, TNUSA Ralf Ulrich TrappeDepartment of Hematology and OncologyDIAKO Ev. Diakonie-Krankenhaus BremenBremen, Germany

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