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Puberty: Physiology and Abnormalities


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Table of Contents

Maturation and Physiology of Hypothalamic Regulation of Gonadal Axis.- Genetic Basis of Puberty.- Hormonal Changes in Childhood and Puberty.- Physical Changes in Puberty.- Growth in Childhood and Puberty.- Bone Development in Children and Adolescents.- Body Weight and Puberty.- The environmental factors and epigenetics of gametogenesis in puberty.- Timing of Puberty and Secular Trend in Human Maturation.- Precocious Puberty.- Constitutional Delayed Puberty.- Pubertal Dysfunction - A Disorder of GnRH Pulsatility.- Pubertal Gynecomastia.-Pubertal Acne.- Adolescent Varicocele.- Polycystic Ovary Syndrome in Adolescent Girls.- Growth Hormone and Steroid Assays’ Problems in Childhood and Puberty.- Psychosocial Development of Adolescents with and without Deviations.- Substance use in adolescence.             

About the Author

Philip Kumanov, MD, PhD, DMedSci, Member (Academician) of European Academy of Andrology (EAA), Professor for Endocrinology, Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria 

Ashok Agarwal, PhD, HCLD (ABB), ELD (ACE), Professor, Lerner College of Medicine and, Case Western Reserve University School of Medicine, American Center for Reproductive Medicine, Department of Urology, Cleveland Clinic Foundation, Cleveland, OH, USA 


“A multi-author, multi-center product which reviews in 19 chapters present knowledge on the genetics and physiology puberty, consequences of early and late puberty and disorders often occurring during adolescence such as gynecomastia, varicocelle, PCOS and possible psychological problems. It is a well organized, concise text, with illustrations, some in color, references after each chapter and an index. Useful for pediatric endocrinologists and pediatricians.” (Pediatric Endocrinology Reviews (PER), vol. 14 (3), March, 2017)

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