Table of Contents

CONTENTS

Contributors

Preface by Steven E. Carsons, Sjögren's Syndrome Foundation Medical and Scientific Advisory Board

Introduction: Why write a book on Sjogren's by Daniel J. Wallace

PART I: INTRODUCTION AND DEFINITIONS

1. Sjögren's Syndrome Foundation
Steven Taylor

2. What is Sjögren's?
Arthur I. Grayzel

3. Who Develops Sjögren's?
Katy M. Setoode and Daniel J. Wallace

PART II: THE PATHOPHYSIOLOGY OF SJÖGREN'S
4. Pathogenesis of Sjögren's Syndrome
Ian R. Mackay

5. Genetics and Sjögren's Syndrome
John A. Ice, Christopher J. Lessard, and Kathy L. Moser

6. Sjögren's Syndrome: An Immunologic Perspective
Robert I. Fox

7. How do These Immunological Events Lead to Dryness in Systemic Disease?
Janine Austin Clayton, Serena Morrison, and Philip C. Fox

PART III: WHERE AND HOW CAN THE BODY BE AFFECTED BY SJÖGREN'S?

8. Generalized Symptoms and Signs of Sjogren's
Steven E. Carsons and Nehad R. Solomon

9. The Internal Organs in Sjogren's
Fotini C. Soliotis, Stuart S. Kassan, and Haralampos M. Moutsopoulos

10. The Central Nervous System and Sjögren's: Vasculitis and Vasculopathy
Elaine Alexander

11. The Gastrointestinal Tract
Matthew Nichols

12. Gynecologic Issues Including Pregnancy
Thomas R. Allan and Ann Parke

13. Lymphoma
Elke Theander and Eva Baecklund

14. Diseases Associated with Sjögren's Syndrome
Frederick B. Vivino

15.
Abha Gulati, Reza Dana, and Gary N. Foulks

16. The Dry Mouth
Ava J. Wu and Troy E. Daniels

17. Salivary Glands, Ears, Nose and Throat
Robert S. Lebovics

18. Lab Work: Blood Tests, Imaging, Biopsies and Beyond
Alan N. Baer

19. Why is Sjögren's Syndrome Difficult to Diagnose?
Robert F. Spiera and Harry Spiera

PART IV: THE MANAGEMENT OF SJÖGREN'S

20. Treatment of Dry Mouth
Philip C. Fox, Mabi I. Singh, and Athena Papas

21. Management of Dry Eye
S. Lance Forstot and Gary N. Foulks

22. Treatment of Other Sicca Symptoms
A. Dry Ears, Nose and Sinuses by Soo Kim Abboud
B. Dry Skin by Theresa L. Ray and John R. Fenyk, Jr.
C. Vaginal Dryness by Elisa Rodriguez Trowbridge

23. Diagnosis and Management of Fatigue
Richa Mishra and Frederick B. Vivino

24. Management of Musculoskeletal and Chronic Pain
Lan Chen

25. Management of Serious Internal Organ Manifestations
Daniel Small

26. Evaluation and Management of the Neurological Manifestations of Sjögren's Syndrome
Steven Mandel, Carla LoPinto-Khoury, Ramon Manon-Espaillat, William Neils, Scott Pello, David Roshal, and Meredith Snapp

27. Complementary and Alternative Therapies for Sjögren's Syndrome
Paul F. Howard and C. Keith Wilkinson

28. Vitamin D and Sjogren's Syndrome
Jeffrey Wilson

29. Testing New Drugs and Future Directions
Young Lee, E. William St. Clair, and Philip L. Cohen

PART V: LIVING WITH SJÖGREN'S

30. Quality of Life and Sjögren's
Barbara M. Segal

31. Lifestyle Issues - Emotional
Teri P. Rumpf and Lynn C. Epstein

32. Enhancing Resilience through Mind/Body Interactions
Margaret Baim

33. Related Topics on Living with Sjögren's
A. Sex by Anne E. Burke
B. Sleep by H. Kenneth Fisher
C. Surgery by Lynn M. Petruzzi
D. Vaccinations by Richard D. Brasington, Jr.

34. Disability and Sjögren's
Thomas D. Sutton, JD and Katherine Morland Hammitt

35. Web, Print and Media Resource Manual

Appendix 1: Glossary
Appendix 2: Products for Sjögren's Patients

About the Author

Daniel J. Wallace, MD, is a Clinical Professor of Medicine at the David Geffen School of Medicine at UCLA based at Cedars-Sinai Medical Center in Los Angeles. His many books include All About Fibromyalgia, All About Osteoarthritis (with Nancy Lane), and The Lupus Book.

Reviews

"The definitive resource on Sjogren's Syndrome-comprehensive, evidence-based, and covers the full spectrum from bench to bedside." --John H. Klippel, MD, President and CEO, Arthritis Foundation
"What a wonderful resource. This handbook will be of great value to people with Sjogren's Syndrome, to the clinicians who care for them, and to their family and friends. It addresses complex medical issues and challenging practical issues with equal clarity and thoroughness, and with genuine concern and compassion." --David Wofsy, MD, President, American College of Rheumatology; George A. Zimmerman Distinguished Professor of Rheumatology, University of
California, San Francisco; Chief, Division of Rheumatology, VA Medical Center
"The Lupus Foundation of America, Inc. (LFA) commends Dr. Daniel Wallace for bringing the latest, medically sound information on Sjogren's Syndrome to individuals with the disease, including people with lupus. The revised edition of The New Sjogren's Syndrome Handbook is a must-read and we applaud the Sjogren's Syndrome Foundation for the quality and excellence of its content." --Sandra C. Raymond, President and CEO, Lupus Foundation of America, Inc.
"The definitive resource on Sjogren's Syndrome-comprehensive, evidence-based, and covers the full spectrum from bench to bedside." --John H. Klippel, MD, President and CEO, Arthritis Foundation
"What a wonderful resource. This handbook will be of great value to people with Sjogren's Syndrome, to the clinicians who care for them, and to their family and friends. It addresses complex medical issues and challenging practical issues with equal clarity and thoroughness, and with genuine concern and compassion." --David Wofsy, MD, President, American College of Rheumatology; George A. Zimmerman Distinguished Professor of Rheumatology, University of
California, San Francisco; Chief, Division of Rheumatology, VA Medical Center
"The Lupus Foundation of America, Inc. (LFA) commends Dr. Daniel Wallace for bringing the latest, medically sound information on Sjogren's Syndrome to individuals with the disease, including people with lupus. The revised edition of The New Sjogren's Syndrome Handbook is a must-read and we applaud the Sjogren's Syndrome Foundation for the quality and excellence of its content." --Sandra C. Raymond, President and CEO, Lupus Foundation of America, Inc.
"Especially helpful to patients and family members is the section on quality of life issues including emotional responses, mind-body interactions, and ways to deal more effectively with problems related to sexual activity, sleep, and issues related to surgery and vaccinations. A comprehensive guide for organizations, support groups and printed materials on Sjogren's syndrome was added to the book along with contact numbers and a grouping of select books on
Sjogren's syndrome." -- Carol Ann Attwood, MLS, AHIP, CHIS, MPH, RN,C Mayo Clinic Arizona, Consumer and Patient Health Information Section