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Targeted Molecular Imaging
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Table of Contents

In Vitro Studies. Small Animal Studies. Radiopharmacology and Radiopharmacy. Case Studies on Developing Target Nonnuclear Probes. Case Studies on Developing Targeted Radiotracers.

About the Author

Dr. Michael J. Welch is Co-Director of the Division of Radiological Sciences and Professor of Radiology at the Washington University School of Medicine's Mallinckrodt Institute of Radiology in St. Louis, Missouri. He is the recipient of several honors, including the Georg Charles de Hevesy Nuclear Medicine Pioneer Award, Paul C. Aebersold Award, American Chemical Society's St. Louis, Midwest and National Awards for Nuclear Chemistry, and the Cassen Award. He has served for many years on the editorial board of the Journal of Nuclear Medicine. Dr. Welch received Bachelor's and graduate degrees from Cambridge University, then earned his doctorate in radiochemistry from the University of London. His primary research involves the development of high resolution PET imaging techniques, with a focus on the developments of novel PET detectors and system suitable for imaging of small laboratory animals. Dr. William C. Eckelman is presently Professor of Radiology at UCSD and the president of Molecular Tracer LLC. A pioneer in Tc-99m radiopharmaceutical development, he and colleagues also developed targeted receptor-binding radiotracers for human use for both SPECT and PET. In addition to his research efforts, Dr. Eckelman has been the editor-in-chief of Nuclear Medicine and Biology since 1985. He received numerous awards including the Paul C. Aebersold Award, the Institute of Clinical PET Distinguished Scientist Award, the American College of Nuclear Physicians Corporate Achievement Award, the Georg deHevesy Nuclear Pioneer Award, and the Great Golden Seal of Padua University for contributions to Radiopharmaceutical Development.

Reviews

"… a timely resource for a rapidly advancing field, giving a comprehensive account of the state of the art in disease modelling, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery. … a helpful tool for all readers involved with targeted molecular imaging, medical chemistry, pharmacology, radiology, and medical physics. It would also be a valuable text for graduate students, postdoctoral fellows, and junior faculty members who are becoming involved in this rapidly expanding field … edited by two masters in the field."
—Luigi Mansi and Davide d’Arienzo, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 40, 2013"… this book is a must for new investigators in the field. Even seasoned investigators are strongly encouraged to consult sections of the book often in order to insure their own studies are complete. Especially important is the interdisciplinary approach utilized in the case studies. This book could also be a valuable resource in graduate classes or as a basis for a continuing education class. The book was written with foresight, such that it can be considered a timeless addition to anyone’s collection. Many, many costly pitfalls can be avoided through thoughtful review of the information contained within this reference."
—Susan Z. Lever, Journal of Labelled Compounds and Radiopharmaceuticals, 2012"This text successfully fulfills its goal by introducing the concepts of molecular imaging agent development and then providing a diverse set of examples of targeted agents. … The strength of this book is its emphasis of case studies that are representative of the various types of translational studies that can be performed using molecular imaging."
—Michael T. Munley, Medical Physics, August 2012

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