Table of Contents

Dedication and Foreword v

Preface vi

Contributors List vii

Section 1: General Topics

1 Introduction: Use, Definitions, History, Concepts, Classification, and Considerations for Anesthesia and Analgesia 3
William J. Tranquilli and Kurt A. Grimm

2 Anesthetic Risk and Informed Consent 11
Dave C. Brodbelt, Derek Flaherty and Glenn R. Pettifer

3 Anesthesia Equipment 23
Craig A. Mosley

4 Monitoring Anesthetized Patients 86
Steve C. Haskins

5 Anesthetic Emergencies and Resuscitation 114
Deborah V. Wilson and Andre C. Shih

6 Euthanasia and Humane Killing 130
Robert E. Meyer

Section 2: Pharmacology

7 General Pharmacology of Anesthetic and Analgesic Drugs 147
Ted Whittem, Thierry Beths and Sebastien H. Bauquier

8 Anticholinergics 178
Phillip Lerche

9 Adrenergic Agents 183
Joanna C. Murrell

10 Sedatives and Tranquilizers 196
David C. Rankin

11 Opioids 207
Butch KuKanich and Ashley J. Wiese

12 Non‐Steroidal Anti‐Inflammatory Drugs 227
Mark G. Papich and Kristin Messenger

13 Anesthetic and Analgesic Adjunctive Drugs 244
Daniel S. J. Pang

14 Muscle Relaxants and Neuromuscular Blockade 260
Robert D. Keegan

15 Injectable Anesthetics 277
Stephanie H. Berry

16 Inhalation Anesthetics 297
Eugene P. Steffey, Khursheed R. Mama and Robert J. Brosnan

17 Local Anesthetics 332
Eva Rioja Garcia

Section 3: Body Fluids and Thermoregulation

18 Acid–Base Physiology 357
William W. Muir

19 Perioperative Thermoregulation and Heat Balance 372
Kurt A. Grimm

20 Treatment of Coagulation and Platelet Disorders 380
Benjamin M. Brainard

21 Clinical Pharmacology and Administration of Fluid, Electrolyte, and Blood Component Solutions 386
Amandeep S. Chohan and Elizabeth B. Davidow

Section 4: Cardiovascular System

22 Cardiovascular Physiology 417
William W. Muir

23 Cardiac Output Measurement 473
Alessio Vigani

24 Anesthesia for Cardiopulmonary Bypass 483
Khursheed R. Mama

25 Cardiac Pacemakers and Anesthesia 490
Barret J. Bulmer

26 Pathophysiology and Anesthetic Management of Patients with Cardiovascular Disease 496
Sandra Z. Perkowski and Mark A. Oyama

Section 5: Respiratory System

27 Physiology, Pathophysiology, and Anesthetic Management of Patients with Respiratory Disease 513
Wayne N. McDonell and Carolyn L. Kerr

Section 6: Nervous System

28 Physiology, Pathophysiology, and Anesthetic Management of Patients with Neurologic Disease 559
Klaus A. Otto

29 Nociception and Pain 584
Carolyn M. McKune, Joanna C. Murrell, Andrea M. Nolan, Kate L. White and Bonnie D. Wright

Section 7: Hepatic System

30 Physiology, Pathophysiology, and Anesthetic Management of Patients with Hepatic Disease 627
Fernando Garcia‐Pereira

Section 8: Gastrointestinal and Endocrine Systems

31 Physiology, Pathophysiology, and Anesthetic Management of Patients with Gastrointestinal and Endocrine Disease 641
Jennifer G. Adams, Juliana Peboni Figueiredo and Thomas K. Graves

Section 9: Urogenital System

32 Physiology, Pathophysiology, and Anesthetic Management of Patients with Renal Disease 681
Stuart C. Clark‐Price and Gregory F. Grauer

33 Anesthetic Considerations for Renal Replacement Therapy 698
Rebecca A. Johnson

34 Anesthetic Considerations During Pregnancy and for the Newborn 708
Marc R. Raffe

Section 10: Comparative Anesthesia and Analgesia

35 Comparative Anesthesia and Analgesia of Dogs and Cats 723
Peter J. Pascoe and Bruno H. Pypendop

36 Anesthesia and Pain Management of Shelter Populations 731
Andrea L. Looney

37 Comparative Anesthesia and Analgesia of Equine Patients 739
Lori A. Bidwell

38 Comparative Anesthesia and Analgesia of Ruminants and Swine 743
HuiChu Lin

39 Comparative Anesthesia and Analgesia of Laboratory Animals 754
Paul A. Flecknell and Aurelie A. Thomas

40 Comparative Anesthesia and Analgesia of Zoo Animals and Wildlife 764
Nigel Anthony Caulkett and Jon M. Arnemo

41 Comparative Anesthesia and Analgesia of Aquatic Mammals 777
David B. Brunson

42 Comparative Anesthesia and Analgesia of Reptiles, Amphibians, and Fishes 784
Cornelia I. Mosley and Craig A. Mosley

43 Comparative Anesthesia and Analgesia of Birds 800
John W. Ludders

Section 11: Anesthesia and Analgesia for Domestic Species

44 Dogs and Cats 819
Richard M. Bednarski

45 Canine and Feline Local Anesthetic and Analgesic Techniques 827
Luis Campoy, Matt Read and Santiago Peralta

46 Horses 857
Regula Bettschart‐Wolfensberger

47 Horses with Colic 867
Cynthia M. Trim and Molly K. Shepard

48 Equine Local Anesthetic and Analgesic Techniques 886
Rachael E. Carpenter and Christopher R. Byron

49 Ruminants 912
Thomas W. Riebold

50 Swine 928
Lais M. Malavasi

51 Ruminant and Swine Local Anesthetic and Analgesic Techniques 941
Alexander Valverde and Melissa Sinclair

Section 12: Anesthesia and Analgesia for Selected Patients or Procedures

52 Ophthalmic Patients 963
Marjorie E. Gross and Luisito S. Pablo

53 Neonatal and Pediatric Patients 983
Tamara L. Grubb, Tania E. Perez Jimenez and Glenn R. Pettifer

54 Senior and Geriatric Patients 988
Tamara L. Grubb Tania E. Perez Jimenez and Glenn R. Pettifer

55 Cancer Patients 993
Timothy M. Fan

56 Orthopedic Patients 1004
Steven C. Budsberg

57 Patient and Anesthetist Safety Considerations for Laserand Radiographic Procedures and Magnetic Resonance Imaging 1015
Julie A. Smith

Index 1027

About the Author

Kurt A. Grimm, DVM, MS, PhD, DACVAA, DACVCP, is theFounder of Veterinary Specialist Services, Conifer, Colorado,USA. Leigh A. Lamont, DVM, MS, DACVAA, is an AssociateProfessor of Anesthesiology at the Atlantic Veterinary College,University of Prince Edward Island, Canada. William J. Tranquilli, DVM, MS, DACVAA, is a ProfessorEmeritus at the University of Illinois College of VeterinaryMedicine and the President of Veterinary Outdoor Recreation andContinuing Education (VORCE) Inc., USA. Stephen A. Greene, DVM, MS, DACVAA, is Professor inAnesthesiology at Washington State University, Pullman, Washington,USA. Sheilah A. Robertson, BVMS (Hons), PhD, DACVAA,DECVAA, DACAW, DECAWBM (WSEL), Specialist in Welfare Science,Ethics and Law, MRCVS, is Associate Professor in Anesthesia atMichigan State University, East Lansing, Michigan, USA.

Reviews

“Overall, this edition has undergone major improvements; the chapters are well written and organized with updated information. This book will be a valuable addition to the library of any veterinarian with an interest in anesthesia and analgesia.”  (Journal of the American Veterinary Medical Association, 15 December 2015) “More than 80 contributors bring their knowledge, experience and in many cases their teaching skills to a tool which represents the latest reference in the field.”  (Vet Nurses Today, 1 October 2015) “This book provides a complete and excellent practice stock text for anaesthesia and analgesia and is so well written that it is a pleasure to read.”  (Veterinary Record, 3 October 2015)

"This comprehensive book is a must have for veterinarians who perform anesthesia or provide analgesia. It is essential for exotic, zoo, and laboratory animal veterinarians and would be very helpful for veterinary students to help augment lectures on these topics." (Choice 2016)

"The fifth Edition of Lumb and Jones Veterinary Anesthesia and Analgesia is a reference book for veterinary practice, to be owned by all clinicians working on a daily basis with anaesthesia of companion animals or different types of challenging patients and procedures requiring anaesthesia. It is highly recommended reading material for all ECVAA residents" (EJCAP Spring 2017)